(N04) Nephrotic syndrome

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1 288 076 in individuals diagnosis nephrotic syndrome confirmed
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9 412 deaths with diagnosis nephrotic syndrome
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1% mortality rate associated with the disease nephrotic syndrome

Diagnosis nephrotic syndrome is diagnosed Men are 19.20% more likely than Women

767 701

Men receive the diagnosis nephrotic syndrome

4 730 (0.6 %)

Died from this diagnosis.

100
95
90
85
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75
70
65
60
55
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35
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15
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520 375

Women receive the diagnosis nephrotic syndrome

4 682 (0.9 %)

Died from this diagnosis.

Risk Group for the Disease nephrotic syndrome - Men and Women aged 5-9

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In Men diagnosis is most often set at age 0-94
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Less common in men the disease occurs at Age 95+Less common in women the disease occurs at Age 95+
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In Women diagnosis is most often set at age 0-94

Disease Features nephrotic syndrome

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Non-contagious
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Moderate individual risk, low public risk
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Nephrotic syndrome - what does this mean

Nephrotic syndrome is a group of symptoms caused by damage to the kidneys, which leads to the leakage of large amounts of protein from the blood into the urine. it is usually caused by a malfunction in the filtering units of the kidneys, known as glomeruli, which results in abnormal amounts of protein being lost in the urine.

What happens during the disease - nephrotic syndrome

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Clinical Pattern

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How does a doctor diagnose

  • Complete medical history and physical examination
  • Urine analysis
  • Blood tests including complete blood count, blood urea nitrogen, creatinine, electrolytes, cholesterol, and triglycerides
  • Kidney biopsy
  • Imaging studies such as ultrasound, CT scan, or MRI
  • Protein excretion test
  • Serum albumin test
  • Urinalysis
  • Kidney function tests

Treatment and Medical Assistance

Main Goal of Treatment: Control the symptoms of Nephrotic Syndrome
  • Prescribe corticosteroids and immunosuppressive drugs to reduce inflammation and suppress the immune system.
  • Administer diuretics to reduce the amount of fluid buildup in the body.
  • Prescribe ACE inhibitors or angiotensin receptor blockers to reduce the risk of kidney damage.
  • Prescribe blood pressure medications to reduce the risk of complications.
  • Prescribe cholesterol-lowering medications to reduce the risk of heart disease.
  • Prescribe antibiotics to treat any infections.
  • Prescribe anti-clotting medications to reduce the risk of blood clots.
  • Prescribe vitamin D supplements to reduce the risk of bone disease.
  • Prescribe iron supplements to reduce the risk of anemia.
  • Prescribe medications to reduce proteinuria.
  • Perform regular blood tests to monitor kidney function.
  • Perform regular urine tests to monitor for proteinuria.
  • Perform regular imaging tests to monitor for kidney damage.
  • Perform regular blood pressure tests to monitor for hypertension.
  • Perform regular cholesterol tests to monitor for heart disease.
  • Educate the patient on lifestyle changes to reduce the risk of complications.
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14 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Nephrotic syndrome - Prevention

Nephrotic syndrome can be prevented by maintaining a healthy lifestyle, including exercising regularly, eating a balanced diet, not smoking, and avoiding alcohol and drugs. it is also important to keep blood pressure and cholesterol levels under control, as well as to monitor for any signs of infection or injury that could lead to kidney damage. additionally, early diagnosis and treatment of any underlying conditions can help to reduce the risk of developing nephrotic syndrome.

Main symptoms of the disease nephrotic syndrome

Tissue edema

(Fluid retention, Swelling, Puffiness, Fluid accumulation, Bloating, Hydrops, Dropsy, Congestion, Inflammation)

Tissue edema is an accumulation of fluid in the interstitial space of the body. It can occur in any part of the body, but is most commonly seen in the extremities, face, and abdomen. It is characterized by swelling, tenderness, and a feeling of tightness in the affected area. It may develop graduall...

Age: any ageAccociated with 132 diseases

General edema

(Swelling, Water retention, Bloating, Puffiness, Inflammation, Fluid retention, Hydrops, Dropsy, Oedema, Hydrothorax)

General edema is swelling caused by excess fluid trapped in the body's tissues. It can affect any part of the body, but is most noticeable in the feet, ankles, legs, hands, and face. It can develop suddenly or gradually. Symptoms range from mild to severe, and may include pain, itching, or a feeling...

Age: any ageAccociated with 50 diseases

Blood in the urine

(Hematuria, Urine with blood, Blood in urine, Discolored urine, Pink urine, Red urine, Maroon urine, Brown urine)

Blood in the urine, also known as hematuria, is a symptom that occurs when red blood cells are present in the urine. It can range from a few drops to a large amount of blood and may be accompanied by pain, a burning sensation, or difficulty urinating. The color of the urine may be pink, red, or brow...

Age: any ageAccociated with 41 diseases

Dark urine

(Black urine, Deep colored urine, Cola colored urine, Tea-colored urine, Brown urine, Amber urine, Rusty urine, Soda-colored urine, Coffee-colored urine)

Dark urine is a symptom of a medical condition where the urine takes on a darker hue, typically yellow or brown. It can be caused by dehydration, liver disease, certain medications, or blood in the urine. It can also be caused by eating certain foods or drinks. Dark urine can develop over time or be...

Age: any ageAccociated with 22 diseases

Nausea

(Upset stomach, Queasiness, Queasy feeling, Stomach discomfort, Gastric unease, Stomach churning, Stomach upset, Stomachache, Feeling sick, Feeling queasy, Stomach queasiness, Feeling nauseous, Feeling nauseated, Nauseousness)

Nausea is an unpleasant feeling in the upper abdomen that may be accompanied by an urge to vomit. It can range from mild to severe and can be accompanied by symptoms such as sweating, dizziness, and increased salivation. Nausea can be caused by a variety of stimuli, including motion sickness, certai...

Age: 1 to 100Accociated with 217 diseases

Headache

(Cephalalgia, Hedache, Pounding head, Throbbing head, Ache, Pounding pain, Throbbing pain, Head pain, Migraine, Tension headache)

Headache is a common symptom that can range from mild to severe. It typically develops gradually and can be localized or generalized. Common types of headache include tension-type, migraine, cluster, and sinus headaches, each with their own unique characteristics and manifestations. Tension-type hea...

Age: 1 to 100Accociated with 244 diseases

Urine color changes

Urine color changes can range from a deep yellow to a light straw color. It can also appear cloudy, dark, or reddish-brown. This symptom can be caused by a variety of factors, from diet to dehydration to certain medications. It can also be a sign of underlying medical conditions, such as infection o...

Age: any ageAccociated with 13 diseases

Weakness

Weakness is a lack of strength and energy that can range from mild to severe. It can be a symptom of a wide range of conditions, including physical and mental exhaustion, chronic illnesses, and certain medications. It can also be caused by a lack of nutrients, dehydration, or an underlying medical c...

Age: any ageAccociated with 291 diseases

Specified forms of the disease

(N04.0) Nephrotic syndrome : minor glomerular abnormality
(N04.1) Nephrotic syndrome : focal and segmental glomerular lesions
(N04.2) Nephrotic syndrome : diffuse membranous glomerulonephritis
(N04.3) Nephrotic syndrome : diffuse mesangial proliferative glomerulonephritis
(N04.4) Nephrotic syndrome : diffuse endocapillary proliferative glomerulonephritis
(N04.5) Nephrotic syndrome : diffuse mesangiocapillary glomerulonephritis
(N04.6) Nephrotic syndrome : dense deposit disease
(N04.7) Nephrotic syndrome : diffuse crescentic glomerulonephritis
(N04.8) Nephrotic syndrome : other
(N04.9) Nephrotic syndrome : unspecified