(A52.2) Asymptomatic neurosyphilis

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74 090 in individuals diagnosis asymptomatic neurosyphilis confirmed
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3 118 deaths with diagnosis asymptomatic neurosyphilis
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4% mortality rate associated with the disease asymptomatic neurosyphilis

Diagnosis asymptomatic neurosyphilis is diagnosed Men are 9.73% more likely than Women

40 649

Men receive the diagnosis asymptomatic neurosyphilis

1 914 (4.7 %)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
33 441

Women receive the diagnosis asymptomatic neurosyphilis

1 204 (3.6 %)

Died from this diagnosis.

Risk Group for the Disease asymptomatic neurosyphilis - Men aged 40-44 and Women aged 30-34

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In Men diagnosis is most often set at age 0-5, 20-74, 80-84
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Less common in men the disease occurs at Age 0-1, 5-19, 75-79, 85-95+Less common in women the disease occurs at Age 0-1, 5-14, 90-95+
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In Women diagnosis is most often set at age 0-5, 15-89

Disease Features asymptomatic neurosyphilis

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Absence or low individual and public risk
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Asymptomatic neurosyphilis - what does this mean

Asymptomatic neurosyphilis is a form of neurosyphilis where the person infected may not show any symptoms, yet the infection is still present in the central nervous system. it is caused by the bacteria treponema pallidum, which is usually transmitted through sexual contact. it can cause severe damage to the brain and spinal cord if left untreated.

What happens during the disease - asymptomatic neurosyphilis

Asymptomatic neurosyphilis is caused by the bacteria treponema pallidum, which is usually transmitted through sexual contact. after infection, the bacteria can spread through the bloodstream and infect the central nervous system, leading to inflammation of the brain and spinal cord. this can cause damage to the nerves and lead to long-term neurological problems, such as dementia and stroke, even if there are no symptoms. in some cases, the bacteria can remain dormant in the body for many years, leading to a diagnosis of asymptomatic neurosyphilis.

Clinical Pattern

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How does a doctor diagnose

  • Physical examination
  • Blood tests (VDRL, FTA-ABS, TP-PA)
  • Cerebrospinal fluid analysis
  • Brain imaging (CT/MRI)
  • Neurological examination
  • Treponema pallidum particle agglutination test (TPPA)
  • Enzyme-linked immunosorbent assay (ELISA)
  • Western blot test

Treatment and Medical Assistance

Main goal of the treatment: Treating Asymptomatic Neurosyphilis
  • Perform a lumbar puncture to assess the cerebrospinal fluid
  • Administer a course of intravenous penicillin
  • Monitor the patient for any signs of neurological symptoms
  • Perform regular neurological assessments
  • Monitor for any signs of ocular or auditory damage
  • Administer a course of corticosteroids to reduce inflammation
  • Monitor for any signs of allergic reactions to the medication
  • Perform regular blood tests to monitor for any signs of infection
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22 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Asymptomatic neurosyphilis - Prevention

The best way to prevent asymptomatic neurosyphilis is to practice safe sex, including using condoms, and to get tested for stds regularly. additionally, individuals should abstain from drug use, especially intravenous drug use, as this increases the risk of contracting the disease.