(D84.0) Lymphocyte function antigen-1 [lfa-1] defect

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263 079 in individuals diagnosis lymphocyte function antigen-1 [lfa-1] defect confirmed
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14 071 deaths with diagnosis lymphocyte function antigen-1 [lfa-1] defect
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5% mortality rate associated with the disease lymphocyte function antigen-1 [lfa-1] defect

Diagnosis lymphocyte function antigen-1 [lfa-1] defect is diagnosed Men are 4.10% more likely than Women

136 927

Men receive the diagnosis lymphocyte function antigen-1 [lfa-1] defect

6 596 (4.8 %)

Died from this diagnosis.

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95
90
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75
70
65
60
55
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45
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5
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126 152

Women receive the diagnosis lymphocyte function antigen-1 [lfa-1] defect

7 475 (5.9 %)

Died from this diagnosis.

Risk Group for the Disease lymphocyte function antigen-1 [lfa-1] defect - Men and Women aged 0-5

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In Men diagnosis is most often set at age 0-89
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Less common in men the disease occurs at Age 90-95+Less common in women the disease occurs at Age 90-95+
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In Women diagnosis is most often set at age 0-89

Disease Features lymphocyte function antigen-1 [lfa-1] defect

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Absence or low individual and public risk
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Lymphocyte function antigen-1 [lfa-1] defect - what does this mean

Lfa-1 defect is a genetic disorder caused by a mutation in the lfa-1 gene, which encodes a protein that is important for the proper functioning of the immune system. this mutation affects the ability of lymphocytes to migrate, interact with other cells, and respond to pathogens, resulting in an impaired immune response.

What happens during the disease - lymphocyte function antigen-1 [lfa-1] defect

Lfa-1 is a type of cell adhesion molecule that is found on the surface of t-cells and other white blood cells. a defect in this molecule can lead to impaired t-cell activation, decreased immune response, and increased susceptibility to infection. the underlying cause of the defect is likely a genetic mutation in the gene responsible for lfa-1 production, leading to an inability of the cell to produce the molecule, or a defect in the structure of the molecule itself.

Clinical Pattern

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How does a doctor diagnose

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Treatment and Medical Assistance

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8 Days of Hospitalization Required
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42 Hours Required for Outpatient Treatment

Lymphocyte function antigen-1 [lfa-1] defect - Prevention

Lfa-1 defect can be prevented by avoiding exposure to environmental toxins, such as cigarette smoke, and by maintaining good hygiene practices, such as washing hands regularly and avoiding contact with people who are infected with infectious diseases. additionally, eating a balanced diet and exercising regularly can help to strengthen the immune system and reduce the risk of developing lfa-1 defects.