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(A81.2) Progressive multifocal leukoencephalopathy
More details coming soon
34 594 in individuals diagnosis progressive multifocal leukoencephalopathy confirmed
23 959 deaths with diagnosis progressive multifocal leukoencephalopathy
69% mortality rate associated with the disease progressive multifocal leukoencephalopathy
Diagnosis progressive multifocal leukoencephalopathy is diagnosed Women are 13.30% more likely than Men
14 997
Men receive the diagnosis progressive multifocal leukoencephalopathy
11 649 (77.7 %)Died from this diagnosis.
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19 597
Women receive the diagnosis progressive multifocal leukoencephalopathy
12 310 (62.8 %)Died from this diagnosis.
Risk Group for the Disease progressive multifocal leukoencephalopathy - Men aged 70-74 and Women aged 65-69
In Men diagnosis is most often set at age 5-9, 20-24, 30-89
Less common in men the disease occurs at Age 0-5, 10-19, 25-29, 90-95+Less common in women the disease occurs at Age 0-1, 5-14, 25-29, 90-95+
In Women diagnosis is most often set at age 0-5, 15-24, 30-89
Disease Features progressive multifocal leukoencephalopathy
Absence or low individual and public risk
Progressive multifocal leukoencephalopathy - what does this mean
Progressive multifocal leukoencephalopathy is caused by a virus, known as jc virus, which infects the brain's white matter and causes inflammation. this inflammation leads to the destruction of myelin, which is the protective coating around nerve cells. as the disease progresses, the damage to the myelin causes a wide range of neurological symptoms, including difficulty with speech, vision, and movement.
What happens during the disease - progressive multifocal leukoencephalopathy
Progressive multifocal leukoencephalopathy is caused by a virus known as the jc polyomavirus, which is found in the blood and other bodily fluids. the virus can enter the body through contact with infected bodily fluids, or through inhalation of aerosolized particles. once inside the body, the virus can infect the white matter of the brain, leading to inflammation and damage to the myelin sheath that surrounds and protects nerve cells. over time, this can lead to a progressive decline in neurological function, including cognitive and motor deficits, and eventually death.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- MRI scan
- CT scan
- Cerebrospinal fluid analysis
- Electroencephalography (EEG)
- Blood tests
- Lumbar puncture
- Brain biopsy
Treatment and Medical Assistance
Main Goal: Reduce the progression of the disease and improve the quality of life of the patient.
- Prescribe medications to reduce inflammation and control the immune system
- Monitor the patient's condition and adjust the treatment plan accordingly
- Administer physical therapy to maintain muscle strength and coordination
- Provide nutritional guidance to ensure adequate nutrition
- Provide emotional support to help the patient cope with the diagnosis
- Educate the patient and their family about the condition and available treatments
- Refer the patient to a neurologist for additional care
46 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Progressive multifocal leukoencephalopathy - Prevention
Progressive multifocal leukoencephalopathy (pml) can be prevented by avoiding certain drugs that suppress the immune system, such as natalizumab, and by maintaining a healthy immune system through regular exercise, healthy eating, and avoiding smoking. vaccines, such as the mmr and varicella, should also be taken to reduce the risk of infection.