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Men receive the diagnosis cytomegaloviral disease, unspecified
1 440 (1.8 %)Died from this diagnosis.
Women receive the diagnosis cytomegaloviral disease, unspecified
2 029 (2.8 %)Died from this diagnosis.
Входными воротами для Cytomegalovirus является слизистая оболочка, преимущественно верхних дыхательных путей и ротоглотки. Инфицирование также может произойти через мочеполовую систему, желудочно-кишечный тракт и другие органы.
В месте внедрения не наблюдается структурных изменений. После того, как вирус проникает в организм, он начинает атаковать моно- и лимфоциты, а также эпителий слюнных желез, почек, легких и других внутренних органов. При этом наблюдается цитомегалия (увеличение пораженных клеток в размерах в 3-4 раза). В ядрах клеток происходит формирование незрелых вирионов.
В ответ на проникновение ЦМВ наблюдается развитие защитной реакции – образуются специфические антитела, и наблюдается гиперчувствительность замедленного типа. Данный процесс сопровождается появлением узелковых образований лимфоцитарных инфильтратов. Клетки, которые были инфицированы, продолжают функционировать, выделяя специальный секрет, обеспечивающий маскировку вируса от защитных функций организма человека.
(Swollen lymph nodes, Enlarged lymph glands, Inflamed lymph nodes, Bulging lymph nodes, Tender lymph nodes, Enlarged lymph nodes, Swollen lymph glands, Inflamed lymph glands, Bulging lymph glands, Tender lymph glands)
Enlarged lymph nodes are swellings in the lymphatic system that can range in size from pea-sized to the size of a golf ball. They can develop in the neck, armpit, or groin and are usually painless. They can be caused by infection, inflammation, or cancer and may be accompanied by fever, night sweats...
(Diminished hunger, Loss of appetite, Lack of appetite, Decreased hunger, Reduced appetite, Anorexia, Poor appetite, Decreased intake, Lack of interest in food)
Decreased appetite is a symptom that can manifest in a variety of ways. It can manifest as a lack of interest in food, difficulty eating, or a lack of hunger. This symptom can develop gradually over time or suddenly. It can be caused by a variety of medical conditions, medications, or psychological ...
Runny nose is a common symptom of a cold or allergies. It is characterized by a clear, watery discharge from the nose and can be accompanied by sneezing, watery eyes, and a sore throat. Runny nose usually begins with a feeling of congestion, followed by a runny discharge that can range from thin and...
(Lymph node ache, Lymph node discomfort, Lymph node soreness, Lymph node tenderness, Lymph node pain, Lymph node agony, Lymph node sore, Lymph node hurting, Lymph node throbbing, Lymph node aching)
Pain in the lymph nodes is an uncomfortable sensation that can range from mild to severe. It may be localized to one area or widespread. It can be accompanied by swelling and tenderness. The pain may become worse when the area is touched or moved. It can develop gradually over time, or it can appear...
(Lymphocyte count increase, High lymphocyte count, Elevated lymphocyte count, Lymphocytic leukocytosis, Increased lymphocyte levels, Lymphocytosis condition, Lymphocytosis disorder)
Lymphocytosis is a condition characterized by an increase in the number of white blood cells called lymphocytes in the blood. It can range from mild to severe and is usually seen as an increase in the number of lymphocytes in the peripheral blood. Symptoms can include fever, fatigue, swollen lymph n...
(Fever with shivering, Fever with trembling, Fever with shaking, Fever with rigors, Fever with quivering, Fever with shuddering, Fever with quaking, Fever with shudder, Fever with trembling rigors, Fever with shuddering fits)
Fever with chills is a common symptom of infection, and is characterized by a sudden onset of high body temperature and shivering. It may be accompanied by other symptoms such as sweating, headache, fatigue, body aches, and general weakness. As the body temperature rises, the patient may experience ...
(Cephalalgia, Hedache, Pounding head, Throbbing head, Ache, Pounding pain, Throbbing pain, Head pain, Migraine, Tension headache)
Headache is a common symptom that can range from mild to severe. It typically develops gradually and can be localized or generalized. Common types of headache include tension-type, migraine, cluster, and sinus headaches, each with their own unique characteristics and manifestations. Tension-type hea...
(High temperature, Fever, Feverishness, Pyrexia, Hyperthermia, Heat, Warmth, Hyperpyrexia, Hyperthermy, Thermalgia)
Elevated temperature is a symptom of illness where the body temperature is higher than normal. It typically appears as a fever, with the temperature ranging from 37-38°C. It is often accompanied by other symptoms such as chills, body aches, and fatigue. Elevated temperature can develop over a few da...
Weakness is a lack of strength and energy that can range from mild to severe. It can be a symptom of a wide range of conditions, including physical and mental exhaustion, chronic illnesses, and certain medications. It can also be caused by a lack of nutrients, dehydration, or an underlying medical c...
(Scratchy throat, Irritated throat, Raw throat, Hoarse throat, Sore throat, Aching throat, Swollen throat, Tender throat, Scratchy feeling in throat, Burning throat)
A sore throat is an inflammation of the throat caused by a virus or bacteria. It usually starts as a scratchy feeling in the throat that progresses to a burning sensation. It is often accompanied by swollen lymph nodes, fever, a runny nose, and a cough. Symptoms can range from mild discomfort to sev...