(C94.5) Острый миелофиброз

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120 090 in individuals diagnosis острый миелофиброз confirmed
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16 667 deaths with diagnosis острый миелофиброз
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14% mortality rate associated with the disease острый миелофиброз

Diagnosis острый миелофиброз is diagnosed Men are 17.58% more likely than Women

70 602

Men receive the diagnosis острый миелофиброз

8 490 (12.0 %)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
40
35
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25
20
15
10
5
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49 488

Women receive the diagnosis острый миелофиброз

8 177 (16.5 %)

Died from this diagnosis.

Risk Group for the Disease острый миелофиброз - Men aged 60-64 and Women aged 70-74

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In Men diagnosis is most often set at age 0-14, 20-95+
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Less common in men the disease occurs at Age 15-19Less common in women the disease occurs at Age 5-9, 15-19, 35-39, 95+
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In Women diagnosis is most often set at age 0-5, 10-14, 20-34, 40-94

Disease Features острый миелофиброз

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Absence or low individual and public risk
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Острый миелофиброз - what does this mean

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What happens during the disease - острый миелофиброз

The pathogenesis of acute myelofibrosis is thought to involve a combination of genetic and environmental factors, including mutations in the jak2 gene, as well as exposure to certain toxins or chemicals. these mutations lead to an increased production of abnormal proteins, which can cause the bone marrow to become fibrotic and unable to produce healthy blood cells. this leads to anemia, fatigue, and other symptoms associated with acute myelofibrosis.

Clinical Pattern

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How does a doctor diagnose

  • Physical examination
  • Blood tests
  • X-ray
  • CT scan
  • MRI scan
  • Ultrasound
  • Bone marrow biopsy
  • Lymph node biopsy

Treatment and Medical Assistance

Main goal: To reduce the symptoms and prevent further damage to the body.
  • Prescribing medications to reduce inflammation and pain
  • Physical therapy to improve muscle strength and flexibility
  • Occupational therapy to help adapt to daily activities
  • Corticosteroid injections to reduce inflammation
  • Surgery to remove affected areas of tissue
  • Plasma exchange to remove harmful antibodies
  • Stem cell transplantation to replace damaged cells
  • Nutritional counseling to ensure proper nutrition
  • Regular follow-up appointments to monitor the disease
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14 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Острый миелофиброз - Prevention

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