(D61.2) Aplastic anaemia due to other external agents

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491 888 in individuals diagnosis aplastic anaemia due to other external agents confirmed
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42 998 deaths with diagnosis aplastic anaemia due to other external agents
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9% mortality rate associated with the disease aplastic anaemia due to other external agents

Diagnosis aplastic anaemia due to other external agents is diagnosed Men are 6.82% more likely than Women

262 713

Men receive the diagnosis aplastic anaemia due to other external agents

22 092 (8.4 %)

Died from this diagnosis.

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95
90
85
80
75
70
65
60
55
50
45
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25
20
15
10
5
0
229 175

Women receive the diagnosis aplastic anaemia due to other external agents

20 906 (9.1 %)

Died from this diagnosis.

Risk Group for the Disease aplastic anaemia due to other external agents - Men and Women aged 65-69

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In Men diagnosis is most often set at age 0-94
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Less common in men the disease occurs at Age 95+in in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features aplastic anaemia due to other external agents

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Absence or low individual and public risk
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Aplastic anaemia due to other external agents - what does this mean

Aplastic anaemia due to other external agents occurs when the body is exposed to certain toxins, such as benzene, certain drugs, and radiation, which can damage the bone marrow and inhibit its ability to produce enough new blood cells. this can lead to a deficiency in red blood cells, white blood cells, and platelets, resulting in anemia, infections, and easy bleeding.

What happens during the disease - aplastic anaemia due to other external agents

Aplastic anaemia due to other external agents is caused by the destruction of the stem cells in the bone marrow. this can be caused by exposure to certain toxins, radiation, or drugs, which can damage the stem cells and prevent them from producing new blood cells. this can lead to a decrease in the number of red blood cells, white blood cells, and platelets, resulting in the symptoms of aplastic anaemia.

Clinical Pattern

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How does a doctor diagnose

  • Complete blood count (CBC)
  • Peripheral blood smear
  • Bone marrow aspiration and biopsy
  • Flow cytometry
  • Cytogenetic analysis
  • Serum iron studies
  • Serum vitamin B12 and folic acid levels
  • Serological tests for hepatitis B and C
  • Liver function tests
  • Serum immunoglobulins
  • Skin tests for tuberculosis
  • Serum protein electrophoresis
  • Thyroid function tests
  • Urinalysis
  • Imaging studies (e.g. chest X-ray, CT scan)

Treatment and Medical Assistance

Main goal of the treatment: Treating aplastic anaemia due to other external agents.
  • Administering immunosuppressive drugs such as cyclosporine and antithymocyte globulin.
  • Performing a bone marrow transplant.
  • Administering growth factors such as erythropoietin and granulocyte-colony stimulating factor.
  • Using androgens such as danazol.
  • Performing blood transfusions.
  • Administering antibiotics to prevent infections.
  • Performing splenectomy.
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17 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Aplastic anaemia due to other external agents - Prevention

To prevent aplastic anaemia due to other external agents, it is important to avoid exposure to toxic chemicals and radiation, as well as to seek prompt medical attention if any symptoms of aplastic anaemia are present. additionally, it is important to practice good hygiene and to get regular check-ups to ensure early diagnosis and treatment of any underlying medical conditions.