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(D53.1) Other megaloblastic anaemias, not elsewhere classified
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208 760 in individuals diagnosis other megaloblastic anaemias, not elsewhere classified confirmed
16 739 deaths with diagnosis other megaloblastic anaemias, not elsewhere classified
8% mortality rate associated with the disease other megaloblastic anaemias, not elsewhere classified
Diagnosis other megaloblastic anaemias, not elsewhere classified is diagnosed Women are 17.07% more likely than Men
86 560
Men receive the diagnosis other megaloblastic anaemias, not elsewhere classified
6 874 (7.9 %)Died from this diagnosis.
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Women receive the diagnosis other megaloblastic anaemias, not elsewhere classified
9 865 (8.1 %)Died from this diagnosis.
Risk Group for the Disease other megaloblastic anaemias, not elsewhere classified - Men aged 75-79 and Women aged 80-84
In Men diagnosis is most often set at age 0-95+
in in men, the disease manifests at any agein in women, the disease manifests at any age
In Women diagnosis is most often set at age 0-95+
Disease Features other megaloblastic anaemias, not elsewhere classified
Absence or low individual and public risk
Other megaloblastic anaemias, not elsewhere classified - what does this mean
Other megaloblastic anaemias, not elsewhere classified, occur when there is a deficiency of either vitamin b12 or folate, which are both essential for the normal development of red blood cells. this leads to an abnormally large number of immature red blood cells in the bloodstream, which can cause anaemia.
What happens during the disease - other megaloblastic anaemias, not elsewhere classified
Other megaloblastic anaemias, not elsewhere classified, are caused by a deficiency in vitamin b12 or folate, which leads to an impaired production of red blood cells. this results in an insufficient amount of oxygen being transported around the body, leading to the classic symptoms of anaemia.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete blood count (CBC)
- Peripheral blood smear
- Bone marrow aspiration and biopsy
- Serum vitamin B12 and folate levels
- Serum methylmalonic acid and homocysteine levels
- Immunologic tests such as anti-intrinsic factor antibody and anti-parietal cell antibody
- Genetic testing for mutations in the vitamin B12 and folate transporter genes
Treatment and Medical Assistance
Main Goal: To treat the underlying cause of Other Megaloblastic Anaemias, not elsewhere classified.
- Identify and address any underlying cause of the anaemia, such as nutritional deficiencies, medications, or other medical conditions.
- Administer vitamin B12 and/or folic acid supplements, as needed.
- Administer iron supplements, as needed.
- Administer blood transfusions, as needed.
- Prescribe antibiotics, as needed.
- Prescribe corticosteroids, as needed.
- Prescribe immunosuppressants, as needed.
- Refer the patient to a hematologist, as needed.
17 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Other megaloblastic anaemias, not elsewhere classified - Prevention
Other megaloblastic anaemias, not elsewhere classified, can be prevented by avoiding certain medications such as anticonvulsants, avoiding alcohol, and eating a balanced diet that includes adequate amounts of vitamin b12 and folate. additionally, individuals should be aware of any underlying medical conditions that may be contributing to the development of the disease.