(D59.6) Haemoglobinuria due to haemolysis from other external causes

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334 581 in individuals diagnosis haemoglobinuria due to haemolysis from other external causes confirmed
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11 068 deaths with diagnosis haemoglobinuria due to haemolysis from other external causes
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3% mortality rate associated with the disease haemoglobinuria due to haemolysis from other external causes

Diagnosis haemoglobinuria due to haemolysis from other external causes is diagnosed Women are 8.82% more likely than Men

152 537

Men receive the diagnosis haemoglobinuria due to haemolysis from other external causes

4 524 (3.0 %)

Died from this diagnosis.

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182 044

Women receive the diagnosis haemoglobinuria due to haemolysis from other external causes

6 544 (3.6 %)

Died from this diagnosis.

Risk Group for the Disease haemoglobinuria due to haemolysis from other external causes - Men aged 0-5 and Women aged 75-79

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In Men diagnosis is most often set at age 0-94
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Less common in men the disease occurs at Age 95+in in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features haemoglobinuria due to haemolysis from other external causes

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Absence or low individual and public risk
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Haemoglobinuria due to haemolysis from other external causes - what does this mean

Haemoglobinuria due to haemolysis from other external causes occurs when red blood cells are broken down and the haemoglobin contained within them is released into the bloodstream. this can be caused by trauma, certain medications, infections, or other medical conditions.

What happens during the disease - haemoglobinuria due to haemolysis from other external causes

Haemoglobinuria due to haemolysis from other external causes is caused by the destruction of red blood cells, resulting in the release of haemoglobin into the urine. this can be caused by a variety of external factors, such as certain drugs, toxins, infections, or physical trauma. the haemolysis can be triggered by an autoimmune response, a deficiency of red cell enzymes, or a genetic defect in the red cell membrane. the released haemoglobin is then cleared out of the body by the kidneys, resulting in haemoglobinuria.

Clinical Pattern

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How does a doctor diagnose

  • Complete Blood Count (CBC)
  • Blood Smear
  • Peripheral Blood Smear
  • Urine Analysis
  • Liver Function Tests
  • Kidney Function Tests
  • Coagulation Panel
  • Serum Bilirubin
  • Serum Creatinine
  • Serum LDH
  • Serum Ferritin
  • Haptoglobin
  • Urine Hemoglobin
  • Urine Urobilinogen
  • Urine Bilirubin
  • Urine Protein
  • Urine Osmolality
  • Urine Sodium
  • Urine Potassium
  • Urine Chloride
  • Urine Calcium
  • Urine Magnesium
  • Urine Glucose
  • Urine pH
  • Urine Microscopy
  • Blood Culture
  • Imaging Tests (CT scan, MRI, Ultrasound)
  • Bone Marrow Biopsy

Treatment and Medical Assistance

Main goal of the treatment: To reduce the rate of haemolysis and to replenish the body's haemoglobin levels.
  • Administering fluids and electrolytes to replace lost fluids and electrolytes
  • Administering blood transfusions to replenish haemoglobin levels
  • Prescribing medications to reduce haemolysis such as corticosteroids and immunosuppressants
  • Administering iron supplements to replenish iron levels
  • Prescribing medications to reduce inflammation and pain
  • Administering antibiotics to treat any underlying infection
  • Providing lifestyle advice to reduce the risk of haemolysis
  • Referring the patient to a specialist for further investigations
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17 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Haemoglobinuria due to haemolysis from other external causes - Prevention

Haemoglobinuria due to haemolysis from other external causes can be prevented by avoiding exposure to toxins, drugs, and other environmental factors that can cause haemolysis, as well as by maintaining a healthy lifestyle and diet. additionally, regular health screenings can help identify potential causes of haemolysis before it becomes a problem.