(D68.0) Von willebrand disease

More details coming soon

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734 830 in individuals diagnosis von willebrand disease confirmed
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26 707 deaths with diagnosis von willebrand disease
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4% mortality rate associated with the disease von willebrand disease

Diagnosis von willebrand disease is diagnosed Women are 9.01% more likely than Men

334 299

Men receive the diagnosis von willebrand disease

11 162 (3.3 %)

Died from this diagnosis.

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400 531

Women receive the diagnosis von willebrand disease

15 545 (3.9 %)

Died from this diagnosis.

Risk Group for the Disease von willebrand disease - Men aged 75-79 and Women aged 80-84

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In Men diagnosis is most often set at age 0-95+
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in in men, the disease manifests at any agein in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features von willebrand disease

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Non-contagious
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High individual risk, low public risk
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Von willebrand disease - what does this mean

Von willebrand disease is an inherited bleeding disorder caused by a deficiency or defect in a protein called von willebrand factor, which helps the blood to clot. people with von willebrand disease have a decreased ability to form blood clots, leading to prolonged bleeding from minor wounds and easy bruising.

What happens during the disease - von willebrand disease

Von willebrand disease is an inherited disorder caused by a deficiency or dysfunction of von willebrand factor (vwf), a protein that helps the blood to clot. this deficiency or dysfunction of vwf can lead to excessive bleeding due to a decreased ability of platelets to adhere to each other and form a clot. the underlying cause of the deficiency or dysfunction is an inherited mutation in the vwf gene, which results in a decrease in the amount or quality of the vwf protein produced.

Clinical Pattern

More details coming soon

How does a doctor diagnose

  • Complete Blood Count (CBC)
  • Bleeding Time Test
  • Platelet Aggregation Test
  • Von Willebrand Factor Activity Test
  • Ristocetin-Induced Platelet Aggregation Test
  • Factor VIII Activity Test
  • Factor VIII Antigen Test
  • Genetic Testing

Treatment and Medical Assistance

Main goal of the treatment: To reduce the symptoms of Von Willebrand disease and improve the patient's quality of life.
  • Regular monitoring of the patient's condition and blood tests.
  • Replacement therapy with von Willebrand factor concentrate or desmopressin.
  • Administration of medications to reduce bleeding such as tranexamic acid, aminocaproic acid or epsilon aminocaproic acid.
  • Treatment of underlying conditions such as anemia.
  • Surgery to repair damaged blood vessels or organs.
  • Blood transfusions to replace lost blood.
  • Platelet transfusions to replace low platelet counts.
  • Physical therapy to improve mobility and reduce pain.
  • Education and counseling about the disease.
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14 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Von willebrand disease - Prevention

Von willebrand disease can be prevented by avoiding contact with people who have been diagnosed with the disorder, practicing good hygiene, and avoiding activities that could cause injury or trauma to the blood vessels. additionally, individuals should be aware of their family history and seek genetic counseling if there is a history of von willebrand disease in the family.

Main symptoms of the disease von willebrand disease

Blood in stool

(Rectal bleeding, Hematochezia, Maroon stool, Gastrointestinal bleeding, Melena, Hemorrhagic stool)

Blood in stool is a symptom of a wide range of medical conditions, from minor to serious. It can appear as bright red blood, black or tarry stools, or blood mixed in with the stool. It can be caused by something as simple as hemorrhoids or as serious as cancer. It usually develops over time and can ...

Age: 1 to 100Accociated with 41 diseases
Rash

Rash

(Eruption, Dermatitis, Skin irritation, Hives, Itching, Inflammation, Redness, Bumps, Blotches, Scaly patch)

A rash is an area of irritated or swollen skin. It may appear as red bumps, patches, or blisters and can be itchy, dry, or painful. It can develop suddenly or over time and can be caused by a variety of factors, including allergies, infections, and irritants. Common rashes include eczema, hives, and...

Age: any ageAccociated with 103 diseases

Bleeding

(Hemorrhaging, Haemorrhage, Hemorrhage, Discharge, Exuding, Ooze, Gush, Seep, Weep, Flow, Drain, Issue, Leak, Emit, Spill, Trickle, Shed, Siphon, Extrude, Squirt, Eject)

Bleeding is the loss of blood from the body. It can occur externally, through the skin, or internally, within the body. It is usually caused by a cut or wound, but can also be caused by a medical condition such as a bleeding disorder. It can range from mild to severe, and can be either acute (short-...

Age: 1 to 100Accociated with 27 diseases

Nose bleed

(Epistaxis, Nasal hemorrhage, Rhinorrhagia, Nasal haemorrhage, Nosebleed)

A nose bleed, also known as epistaxis, is a common symptom that occurs when the small blood vessels in the nose burst and bleed. It can occur suddenly, or develop gradually over time. Symptoms may include a sudden onset of bright red blood flowing from the nose, or a slow trickle of blood. Nose blee...

Age: 1 to 100Accociated with 26 diseases