(D68.8) Other specified coagulation defects

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734 830 in individuals diagnosis other specified coagulation defects confirmed
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26 707 deaths with diagnosis other specified coagulation defects
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4% mortality rate associated with the disease other specified coagulation defects

Diagnosis other specified coagulation defects is diagnosed Women are 9.01% more likely than Men

334 299

Men receive the diagnosis other specified coagulation defects

11 162 (3.3 %)

Died from this diagnosis.

100
95
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75
70
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55
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400 531

Women receive the diagnosis other specified coagulation defects

15 545 (3.9 %)

Died from this diagnosis.

Risk Group for the Disease other specified coagulation defects - Men aged 75-79 and Women aged 80-84

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In Men diagnosis is most often set at age 0-95+
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in in men, the disease manifests at any agein in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features other specified coagulation defects

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Absence or low individual and public risk
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Other specified coagulation defects - what does this mean

Other specified coagulation defects are a group of disorders caused by deficiencies in the production or function of clotting factors, resulting in prolonged bleeding times and increased risk of bleeding. it can also be caused by abnormal platelet function or by increased fibrinolysis.

What happens during the disease - other specified coagulation defects

Other specified coagulation defects are a group of disorders that result from a deficiency or dysfunction of the proteins involved in the clotting cascade. this can lead to either a decrease in clotting factors or an abnormality in the structure or function of the clotting factors, both of which can cause an increased risk of bleeding. in some cases, the underlying cause of the disorder may be inherited, while in other cases it may be acquired due to environmental factors or medications.

Clinical Pattern

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How does a doctor diagnose

  • Complete Blood Count (CBC)
  • Platelet count
  • Prothrombin time (PT) and International Normalized Ratio (INR)
  • Partial thromboplastin time (PTT)
  • Activated Partial Thromboplastin Time (APTT)
  • Fibrinogen level
  • Factor assays (e.g. Factor V, Factor VIII, Factor IX)
  • Antithrombin III (AT-III) levels
  • D-Dimer test
  • Genetic testing

Treatment and Medical Assistance

Main goal of the treatment: To correct the underlying cause of the Other Specified Coagulation Defects.
  • Administering vitamin K to replenish the body's clotting factors
  • Administering fresh frozen plasma to replenish the body's clotting factors
  • Administering desmopressin to increase the body's clotting factors
  • Administering antifibrinolytic drugs to reduce blood clot breakdown
  • Prescribing anticoagulant medications to reduce the risk of clotting
  • Performing a platelet transfusion to increase the number of platelets
  • Performing a factor VIII transfusion to increase the amount of factor VIII
  • Performing a factor IX transfusion to increase the amount of factor IX
  • Performing a factor XIII transfusion to increase the amount of factor XIII
  • Undergoing genetic testing to identify the underlying cause of the disorder
  • Undergoing a liver biopsy to identify any underlying liver disease
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14 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Other specified coagulation defects - Prevention

Other specified coagulation defects can be prevented by maintaining a healthy lifestyle, avoiding alcohol, smoking and other drugs, eating a balanced diet, and exercising regularly. additionally, regular check-ups with a medical professional should be undertaken to monitor any changes in health.