(D75.2) Эссенциальный тромбоцитоз

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470 059 in individuals diagnosis эссенциальный тромбоцитоз confirmed
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9 064 deaths with diagnosis эссенциальный тромбоцитоз
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2% mortality rate associated with the disease эссенциальный тромбоцитоз

Diagnosis эссенциальный тромбоцитоз is diagnosed Men are 9.72% more likely than Women

257 882

Men receive the diagnosis эссенциальный тромбоцитоз

5 068 (2.0 %)

Died from this diagnosis.

100
95
90
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75
70
65
60
55
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15
10
5
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212 177

Women receive the diagnosis эссенциальный тромбоцитоз

3 996 (1.9 %)

Died from this diagnosis.

Risk Group for the Disease эссенциальный тромбоцитоз - Men aged 60-64 and Women aged 75-79

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In Men diagnosis is most often set at age 0-94
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Less common in men the disease occurs at Age 95+Less common in women the disease occurs at Age 95+
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In Women diagnosis is most often set at age 0-94

Disease Features эссенциальный тромбоцитоз

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Absence or low individual and public risk
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Эссенциальный тромбоцитоз - what does this mean

Essential thrombocythemia (et) is a disorder of the blood caused by an overproduction of platelets, which are necessary for normal blood clotting. it is caused by a mutation in the jak2 gene, which leads to an overproduction of platelets, resulting in an increased risk of blood clots, stroke, and heart attack.

What happens during the disease - эссенциальный тромбоцитоз

Essential thrombocythemia is a myeloproliferative disorder caused by an abnormal increase in the production of platelets in the bone marrow. it is believed to be caused by a mutation of the jak2 gene, which is responsible for regulating the production of platelets. the mutation causes an overproduction of platelets, leading to an increased risk of thrombosis and other related complications.

Clinical Pattern

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How does a doctor diagnose

  • Complete Blood Count (CBC)
  • Peripheral Blood Smear
  • Bone Marrow Aspirate and Biopsy
  • Flow Cytometry
  • Genetic Testing
  • Ultrasound Scan
  • Liver Function Tests
  • Kidney Function Tests
  • Serum Protein Electrophoresis

Treatment and Medical Assistance

Main goal: Reduce the number of essential thrombocythemia (ET) cells in the body.
  • Prescribing medications to reduce the number of ET cells in the body, such as hydroxyurea, anagrelide, and interferon-alpha.
  • Performing regular blood tests to monitor the levels of ET cells in the body.
  • Recommending lifestyle changes, such as avoiding alcohol and smoking.
  • Performing regular physical examinations to check for any complications.
  • Referring the patient to a hematologist for further evaluation.
  • Performing a bone marrow biopsy to confirm the diagnosis.
  • Performing radiation therapy to reduce the number of ET cells in the body.
  • Performing a stem cell transplant to replace the damaged bone marrow.
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13 Days of Hospitalization Required
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44 Hours Required for Outpatient Treatment

Эссенциальный тромбоцитоз - Prevention

The best way to prevent essential thrombocythemia is to maintain a healthy lifestyle, including regular exercise, a balanced diet, and avoiding smoking and alcohol. additionally, it is important to manage any risk factors, such as high blood pressure, diabetes, or obesity, and to monitor blood tests regularly to detect any changes in platelet levels.