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(D81.8) Other combined immunodeficiencies
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37 763 in individuals diagnosis other combined immunodeficiencies confirmed
2 729 deaths with diagnosis other combined immunodeficiencies
7% mortality rate associated with the disease other combined immunodeficiencies
Diagnosis other combined immunodeficiencies is diagnosed Men are 25.48% more likely than Women
23 693
Men receive the diagnosis other combined immunodeficiencies
926 (3.9 %)Died from this diagnosis.
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14 070
Women receive the diagnosis other combined immunodeficiencies
1 803 (12.8 %)Died from this diagnosis.
Risk Group for the Disease other combined immunodeficiencies - Men aged 20-24 and Women aged 0-5
In Men diagnosis is most often set at age 0-14, 20-89
Less common in men the disease occurs at Age 15-19, 90-95+Less common in women the disease occurs at Age 55-59, 90-95+
In Women diagnosis is most often set at age 0-54, 60-89
Disease Features other combined immunodeficiencies
Absence or low individual and public risk
Other combined immunodeficiencies - what does this mean
Other combined immunodeficiencies are a group of rare, inherited disorders caused by genetic mutations that affect the body's ability to produce the proteins necessary for a functioning immune system. these disorders can be caused by a single mutation or by a combination of mutations, and can range from mild to severe. symptoms can include frequent infections, low white blood cell count, and poor response to vaccinations.
What happens during the disease - other combined immunodeficiencies
Other combined immunodeficiencies are a group of rare inherited disorders caused by mutations in genes that are important for the development and functioning of the immune system. these mutations disrupt the normal production of white blood cells, which are responsible for fighting infection, resulting in recurrent infections, increased susceptibility to certain types of cancer, and other complications. in some cases, the mutations also affect the production of other molecules involved in the immune response, such as cytokines, which can further impair the body’s ability to fight infection.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete blood count (CBC)
- Thyroid function test
- Liver function test
- Immunoglobulin levels
- T-cell subset analysis
- Cellular immunity tests
- Molecular genetic testing
- X-ray or CT scan of the chest
- Bone marrow biopsy
- Lymph node biopsy
Treatment and Medical Assistance
Main goal of the treatment: To treat Other combined immunodeficiencies.
- Identification of genetic mutations causing immunodeficiencies.
- Identification of environmental factors that may contribute to the development of immunodeficiencies.
- Replacement of deficient immune components.
- Administration of immunoglobulins.
- Administration of antibiotics.
- Administration of antiviral drugs.
- Administration of antifungal drugs.
- Administration of anti-inflammatory drugs.
- Administration of immunomodulating drugs.
- Administration of stem cell therapy.
- Administration of gene therapy.
19 Days of Hospitalization Required
48 Hours Required for Outpatient Treatment
Other combined immunodeficiencies - Prevention
Other combined immunodeficiencies can be prevented by avoiding exposure to infections, following a healthy lifestyle, and getting regular immunizations. it is important to practice good hygiene, avoid contact with people who are ill, and eat a balanced diet. vaccines are also important for preventing infections that can lead to these conditions.