DocSym
β
Searchsearch
Search
(D89.0) Polyclonal hypergammaglobulinaemia
More details coming soon
174 863 in individuals diagnosis polyclonal hypergammaglobulinaemia confirmed
7 103 deaths with diagnosis polyclonal hypergammaglobulinaemia
4% mortality rate associated with the disease polyclonal hypergammaglobulinaemia
Diagnosis polyclonal hypergammaglobulinaemia is diagnosed Women are 22.25% more likely than Men
67 982
Men receive the diagnosis polyclonal hypergammaglobulinaemia
4 498 (6.6 %)Died from this diagnosis.
100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
106 881
Women receive the diagnosis polyclonal hypergammaglobulinaemia
2 605 (2.4 %)Died from this diagnosis.
Risk Group for the Disease polyclonal hypergammaglobulinaemia - Men aged 60-64 and Women aged 50-54
In Men diagnosis is most often set at age 0-89
Less common in men the disease occurs at Age 90-95+Less common in women the disease occurs at Age 90-95+
In Women diagnosis is most often set at age 0-89
Disease Features polyclonal hypergammaglobulinaemia
Absence or low individual and public risk
Polyclonal hypergammaglobulinaemia - what does this mean
Polyclonal hypergammaglobulinaemia is a condition in which an individual has abnormally high levels of antibodies (gamma globulins) in their blood. this is caused by an overactive immune system, which results in the production of excessive amounts of antibodies in response to a variety of antigens. this can lead to symptoms such as fatigue, weight loss, and recurrent infections.
What happens during the disease - polyclonal hypergammaglobulinaemia
Polyclonal hypergammaglobulinaemia is a disorder in which the body produces too many antibodies, known as immunoglobulins. this is caused by an over-stimulation of the immune system, which can be triggered by a variety of factors such as infections, autoimmune diseases, or certain medications. this over-stimulation causes an increase in the production of immunoglobulins, which can lead to an increase in the amount of gamma globulins in the blood. as a result, the body is unable to effectively fight off infections and other foreign invaders, leading to an increased risk of infection and other illnesses.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete blood count (CBC)
- Serum protein electrophoresis (SPE)
- Immunoglobulin quantification
- Flow cytometry
- Immunofixation electrophoresis (IFE)
- Antinuclear antibody (ANA) testing
- Quantitative immunoglobulin levels
- Bone marrow biopsy
- Genetic testing
Treatment and Medical Assistance
Main goal of the treatment: To reduce the levels of hypergammaglobulinaemia.
- Monitoring of symptoms and laboratory tests
- Administering immunosuppressive drugs
- Administering immunoglobulin replacement therapy
- Administering corticosteroids
- Administering monoclonal antibodies
- Administering plasma exchange
- Administering chemotherapy
- Administering radiation therapy
- Administering stem cell transplantation
11 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Polyclonal hypergammaglobulinaemia - Prevention
Polyclonal hypergammaglobulinaemia is a rare condition, and the best way to prevent it is to avoid any lifestyle factors that may increase the risk of developing it, such as smoking, drinking alcohol, and exposure to environmental toxins. additionally, it is important to maintain a healthy lifestyle, including eating a balanced diet, exercising regularly, and getting adequate sleep. vaccinations should also be kept up to date, as this can help to reduce the risk of certain infections that may lead to polyclonal hypergammaglobulinaemia.