(E22.1) Hyperprolactinaemia
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Diagnosis hyperprolactinaemia is diagnosed Women are 67.94% more likely than Men
Men receive the diagnosis hyperprolactinaemia
2 121 (1.8 %)Died from this diagnosis.
Women receive the diagnosis hyperprolactinaemia
1 143 (0.2 %)Died from this diagnosis.
Risk Group for the Disease hyperprolactinaemia - Men aged 55-59 and Women aged 25-29
Disease Features hyperprolactinaemia
Hyperprolactinaemia - what does this mean
What happens during the disease - hyperprolactinaemia
Избыточное содержание в крови пролактина по механизму отрицательной обратной связи подавляет секрецию гонадолиберина в гипоталамусе, что приводит к снижению выработки лютеинизирующего и фолликулостимулирующего гормонов. В результате развивается недостаточность половых гормонов, гипоплазия наружных половых органов (гипогонадизм), активная пролиферация секреторного аппарата молочной железы, усиление лактогенеза и лактации (галакторея), особенно у женщин.
Длительно сохраняющаяся гиперпролактинемия стимулирует процессы резорбции костной ткани, что снижает ее минеральную плотность (остеопороз). Лептинорезистентность, дефицит адипонектина и гипогонадизм способствуют отложению жира в подкожно-жировой клетчатке и повышению содержания в сыворотке холестериновых фракций. Отмечается умеренная гиперпродукция андрогенов сетчатой зоной коры надпочечников.
Clinical Pattern
How does a doctor diagnose
- Physical examination
- Blood tests to measure prolactin levels
- CT scan of the brain
- MRI of the brain
- Thyroid function tests
- Gonadal hormone tests
- Drug screening
- Genetic testing
Treatment and Medical Assistance
- Prescribing medications such as dopamine agonists and bromocriptine
- Surgery to remove the tumor causing the hyperprolactinemia
- Lifestyle changes such as reducing stress levels and avoiding certain medications
- Dietary changes such as avoiding alcohol and caffeine
- Regular exercise
- Regular follow-up visits with the doctor
Hyperprolactinaemia - Prevention
Main symptoms of the disease hyperprolactinaemia
Psychosis
(Psychotic disorder, Mental illness, Delusional disorder, Schizophrenia, Mania, Psychotic break, Hallucinations, Paranoia, Psychotic episode, Psychotic symptoms)
Psychosis is a mental disorder characterized by a disconnection from reality. Symptoms may include delusions, hallucinations, disorganized thinking, speech, and behavior. It can develop gradually or suddenly, and can be triggered by stress, substance use, or a physical illness. Symptoms may manifest...
Gynecomastia
(Male breast enlargement, Man boobs, Male breast development, Glandular mammary hypertrophy, Pseudogynecomastia, Adipomastia, Mammary hypertrophy, Feminizing mammary gland hyperplasia)
Gynecomastia is a condition in which the breasts become enlarged in males due to a hormonal imbalance. It is characterized by swelling of the breast tissue and can occur in one or both breasts. It is most common in teenage boys, but can occur in adults as well. It usually develops gradually over tim...
Breast milk production
(Breastfeeding, Lactation, Nursing, Milk production, Galactopoiesis, Lactogenesis, Lactogenesis ii, Galactorrhea)
Breast milk production is the process of producing milk from the mammary glands. It usually begins after a few days of giving birth and continues until weaning. It is characterized by swelling and tenderness of the breasts, increased blood flow to the area, and a milky discharge from the nipples. Ov...
Decreased sex drive
(Diminished libido, Lack of libido, Loss of libido, Low sex drive, Reduced sex drive, Decreased sexual desire, Lack of sexual desire, Loss of sexual desire, Low sexual desire)
Decreased sex drive is a common symptom that can manifest in many ways. It can manifest as a lack of interest in sex, difficulty becoming aroused, or difficulty achieving orgasm. It can also manifest as a lack of sexual fantasies or thoughts. It can develop gradually over time, or it can be sudden a...
Excess hair growth
(Hypertrichosis, Hirsutism, Excessive hair growth, Unwanted hair growth, Facial hair growth, Excessive body hair, Abnormal hair growth, Unusual hair growth, Excess body hair, Hypertrichiasis)
Excess hair growth is a common symptom of hormonal imbalances. It can appear as increased facial and body hair, in both men and women. It usually starts with a slight increase in the amount of hair, and then progresses to a more noticeable amount of hair. It can manifest as thick, coarse hairs on th...
Acne
(Pimples, Zits, Blemishes, Breakouts, Whiteheads, Blackheads, Cysts, Spots, Rash, Papules, Pustules)
Acne is a common skin condition characterized by pimples, blackheads, and whiteheads. It typically develops during puberty due to hormonal changes and can affect people of all ages. It is caused by the overproduction of sebum, which can clog pores and lead to the formation of comedones (whiteheads a...
Abnormal weight gain
(Unexplained weight gain, Unusual weight gain, Unwanted weight gain, Unexpected weight gain, Unusual increase in weight, Uncontrolled weight gain, Untimely weight gain, Uncontrolled increase in weight, Unintended weight gain, Unplanned weight gain)
Abnormal weight gain is an increase in body weight that is not due to an increase in muscle mass. It is often caused by an unhealthy diet, lack of exercise, or a combination of both. It can lead to various health problems, including an increased risk of diabetes, heart disease, and stroke. Symptoms ...
Menstrual irregularity
Menstrual irregularity is a common symptom experienced by women of all ages. It is characterized by changes in the duration, frequency, and intensity of menstrual bleeding. It can range from infrequent, light periods to prolonged and heavy periods. It can also include spotting between periods, misse...