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(E24.0) Pituitary-dependent cushing disease
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214 832 in individuals diagnosis pituitary-dependent cushing disease confirmed
3 085 deaths with diagnosis pituitary-dependent cushing disease
1% mortality rate associated with the disease pituitary-dependent cushing disease
Diagnosis pituitary-dependent cushing disease is diagnosed Women are 42.10% more likely than Men
62 196
Men receive the diagnosis pituitary-dependent cushing disease
915 (1.5 %)Died from this diagnosis.
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152 636
Women receive the diagnosis pituitary-dependent cushing disease
2 170 (1.4 %)Died from this diagnosis.
Risk Group for the Disease pituitary-dependent cushing disease - Men aged 20-24 and Women aged 55-59
In Men diagnosis is most often set at age 0-1, 5-84
Less common in men the disease occurs at Age 0-5, 85-95+Less common in women the disease occurs at Age 90-95+
In Women diagnosis is most often set at age 0-89
Disease Features pituitary-dependent cushing disease
Absence or low individual and public risk
Pituitary-dependent cushing disease - what does this mean
Pituitary-dependent cushing disease occurs when the pituitary gland produces too much of the hormone cortisol, which causes an excess of cortisol in the body. this can lead to symptoms such as weight gain, high blood pressure, thinning of the skin, and easy bruising.
What happens during the disease - pituitary-dependent cushing disease
Pituitary-dependent cushing disease is caused by a tumor in the pituitary gland that produces excess amounts of the hormone cortisol. this excess cortisol then stimulates the adrenal glands to produce more cortisol, resulting in an elevated level of cortisol in the body. this elevated level of cortisol can lead to a variety of symptoms including weight gain, fatigue, muscle weakness, high blood pressure, and depression.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Physical examination and history taking
- Blood tests to measure cortisol levels
- Imaging tests such as MRI or CT scan
- Urine tests to measure cortisol levels
- Dexamethasone suppression test
- CRH stimulation test
- Petrosal sinus sampling
Treatment and Medical Assistance
Main goal of the treatment: To reduce the production of cortisol and restore the normal functioning of the pituitary gland.
- Prescribing medications to suppress cortisol production
- Surgery to remove the tumor causing the disease
- Radiation therapy to shrink the tumor
- Administering medications to reduce the size of the tumor
- Administering medications to reduce inflammation and pain
- Regular monitoring of cortisol levels
- Regular monitoring of hormone levels
- Regular monitoring of blood sugar levels
- Regular monitoring of blood pressure levels
- Regular monitoring of body weight
- Regular monitoring of sleep patterns
- Regular physical activity
- Healthy eating habits
- Stress management
14 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Pituitary-dependent cushing disease - Prevention
The best way to prevent pituitary-dependent cushing disease is to maintain a healthy lifestyle, including regular exercise and a balanced diet. it is also important to monitor hormone levels, as well as to identify and treat any underlying medical conditions that may be contributing to the development of the disease. additionally, it is important to avoid any activities or medications that may cause a disruption in the body's hormonal balance.