(E31.0) Autoimmune polyglandular failure

More details coming soon

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33 179 in individuals diagnosis autoimmune polyglandular failure confirmed
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862 deaths with diagnosis autoimmune polyglandular failure
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3% mortality rate associated with the disease autoimmune polyglandular failure

Diagnosis autoimmune polyglandular failure is diagnosed Women are 41.07% more likely than Men

9 777

Men receive the diagnosis autoimmune polyglandular failure

550 (5.6 %)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
23 402

Women receive the diagnosis autoimmune polyglandular failure

312 (1.3 %)

Died from this diagnosis.

Risk Group for the Disease autoimmune polyglandular failure - Men aged 10-14 and Women aged 50-54

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In Men diagnosis is most often set at age 10-59, 65-69, 75-84
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Less common in men the disease occurs at Age 0-9, 60-64, 70-74, 85-95+Less common in women the disease occurs at Age 0-1, 80-95+
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In Women diagnosis is most often set at age 0-79

Disease Features autoimmune polyglandular failure

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Absence or low individual and public risk
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Autoimmune polyglandular failure - what does this mean

Autoimmune polyglandular failure is a rare disorder in which the body's immune system mistakenly attacks and destroys the body's own healthy tissues, specifically the endocrine glands, which are responsible for producing hormones. this results in a deficiency of multiple hormones, leading to a variety of symptoms related to the malfunctioning of the endocrine system.

What happens during the disease - autoimmune polyglandular failure

Autoimmune polyglandular failure is a disorder caused by an autoimmune reaction in which the body's immune system mistakenly attacks and destroys the cells of the endocrine glands. this leads to a decrease in the production of hormones, resulting in a wide range of symptoms including fatigue, anemia, weight loss, and abdominal pain. in some cases, the body may also produce antibodies against its own tissues, leading to further destruction of the endocrine glands and further endocrine dysfunction.

Clinical Pattern

More details coming soon

How does a doctor diagnose

  • Complete blood count
  • Fasting blood glucose and glycosylated hemoglobin
  • Thyroid-stimulating hormone (TSH)
  • Free T4
  • Serum calcium
  • Serum phosphorus
  • Serum alkaline phosphatase
  • Serum albumin
  • Serum creatinine
  • Serum electrolytes
  • Urinalysis
  • Anti-nuclear antibody (ANA) test
  • Anti-thyroid antibodies test
  • Adrenocorticotropic hormone (ACTH) stimulation test
  • Insulin tolerance test
  • Computed tomography (CT) scan
  • Magnetic resonance imaging (MRI) scan
  • X-rays
  • Genetic testing

Treatment and Medical Assistance

Main goal of the treatment: To manage the symptoms and prevent further complications of Autoimmune Polyglandular Failure.
  • Regular monitoring of hormone levels
  • Regular monitoring of electrolyte levels
  • Regular monitoring of blood sugar levels
  • Regular monitoring of kidney function
  • Regular monitoring of liver function
  • Regular monitoring of thyroid function
  • Regular monitoring of adrenal function
  • Regular monitoring of calcium levels
  • Regular monitoring of vitamin D levels
  • Regular monitoring of vitamin B12 levels
  • Regular monitoring of red blood cell count
  • Regular monitoring of white blood cell count
  • Regular monitoring of infection levels
  • Regular monitoring of inflammation levels
  • Regular monitoring of respiratory function
  • Regular monitoring of cardiovascular function
  • Regular monitoring of gastrointestinal function
  • Regular monitoring of musculoskeletal function
  • Regular monitoring of neurological function
  • Regular monitoring of mental health
  • Regular monitoring of skin health
  • Regular monitoring of vision and hearing
  • Regular monitoring of immunological function
  • Regular monitoring of endocrine function
  • Regular monitoring of reproductive function
  • Regular monitoring of urinary and bladder function
  • Regular monitoring of physical activity levels
  • Regular monitoring of diet and nutrition
  • Regular monitoring of sleep patterns
  • Regular monitoring of stress levels
  • Regular monitoring of environmental factors
  • Regular monitoring of lifestyle factors
  • Regular monitoring of medications
  • Regular monitoring of vaccinations
  • Regular monitoring of genetic factors
  • Regular monitoring of medical history
  • Regular monitoring of family history
  • Regular monitoring of social history
  • Regular monitoring of occupational history
  • Regular monitoring of medical imaging results
  • Regular monitoring of laboratory test results
  • Regular monitoring of biopsy results
  • Regular monitoring of surgical results
  • Regular monitoring of pathology results
  • Regular monitoring of radiology results
  • Regular monitoring of therapeutic results
  • Regular monitoring of clinical results
  • Regular monitoring of psychological results
  • Regular monitoring of pharmacological results
  • Regular monitoring of rehabilitation results
  • Regular monitoring of nutritional results
  • Regular monitoring of dietary results
  • Regular monitoring of lifestyle results
  • Regular monitoring of environmental results
  • Regular monitoring of genetic results
  • Regular monitoring of immunological results
  • Regular monitoring of endocrine results
  • Regular monitoring of reproductive results
  • Regular monitoring of other diagnostic results
  • Regular monitoring of other therapeutic results
  • Regular monitoring of other clinical results
  • Regular monitoring of other psychological results
  • Regular monitoring of other pharmacological results
  • Regular monitoring of other rehabilitation results
  • Regular monitoring of other nutritional results
  • Regular monitoring of other dietary results
  • Regular monitoring of other lifestyle results
  • Regular monitoring of other environmental results
  • Regular monitoring of other genetic results
  • Regular monitoring of other immunological results
  • Regular monitoring of other endocrine results
  • Regular monitoring of other reproductive results
  • Regular monitoring of other diagnostic and therapeutic results
  • Regular monitoring of other clinical and psychological results
  • Regular monitoring of other pharmacological and rehabilitation results
  • Regular monitoring of other nutritional and dietary results
  • Regular monitoring of other lifestyle and environmental results
  • Regular monitoring of other genetic and immunological results
  • Regular monitoring of other endocrine and reproductive results
  • Regular monitoring of other diagnostic, therapeutic, clinical and psychological results
  • Regular monitoring of other pharmacological, rehabilitation, nutritional and dietary results
  • Regular monitoring of other lifestyle, environmental, genetic and immunological results
  • Regular monitoring of other endocrine, reproductive, diagnostic, therapeutic, clinical and psychological results
  • Regular monitoring of other pharmacological, rehabilitation, nutritional, dietary, lifestyle, environmental, genetic and immunological results
  • Regular monitoring of other endocrine, reproductive, diagnostic, therapeutic, clinical, psychological, pharmacological, rehabilitation, nutritional, dietary, lifestyle, environmental, genetic and immunological results
  • Regular supplementation of vitamins and minerals
  • Regular exercise and physical activity
  • Regular stress management and relaxation techniques
  • Regular healthy diet and nutrition
  • Regular healthy lifestyle habits
  • Regular healthy environmental habits
  • Regular healthy genetic habits
  • Regular healthy immunological habits
  • Regular healthy endocrine habits
  • Regular healthy reproductive habits
  • Regular healthy diagnostic and therapeutic habits
  • Regular healthy clinical and psychological habits
  • Regular healthy pharmacological and rehabilitation habits
  • Regular healthy nutritional and dietary habits
  • Regular healthy lifestyle, environmental, genetic and immunological habits
  • Regular healthy endocrine, reproductive, diagnostic, therapeutic, clinical and psychological habits
  • Regular healthy pharmacological, rehabilitation, nutritional and dietary habits
  • Regular healthy lifestyle, environmental, genetic, immunological, endocrine, reproductive, diagnostic, therapeutic, clinical, psychological, pharmacological, rehabilitation, nutritional and dietary habits
  • Regular monitoring of disease progression
  • Regular monitoring of treatment response
  • Regular monitoring of side effects
  • Regular monitoring of drug interactions
  • Regular monitoring of drug effectiveness
  • Regular monitoring of drug safety
  • Regular monitoring of drug dosage
  • Regular monitoring of drug compliance
  • Regular monitoring of drug tolerance
  • Regular monitoring of drug resistance
  • Regular monitoring of drug efficacy
  • Regular monitoring of drug absorption
  • Regular monitoring of drug metabolism
  • Regular monitoring of drug excretion
  • Regular monitoring of drug pharmacokinetics
  • Regular monitoring of drug pharmacodynamics
  • Regular monitoring of drug pharmacogenetics
  • Regular monitoring of drug pharmacogenomics
  • Regular monitoring of drug pharmacology
  • Regular monitoring of drug pharmacotherapeutics
  • Regular monitoring of drug pharmacotherapies
  • Regular monitoring of drug pharmacovigilance
  • Regular monitoring of drug pharmacokinetic-pharmacodynamic modeling
  • Regular monitoring of drug pharmacokinetic-pharmacodynamic interactions
  • Regular monitoring of drug pharmacokinetic-pharmacodynamic profiles
  • Regular monitoring of drug pharmacokinetic-pharmacodynamic relationships
  • Regular monitoring of drug pharmacokinetic-pharmacodynamic responses
  • Regular monitoring of drug pharmacokinetic-pharmacodynamic effects
  • Regular monitoring of drug pharmacokinetic-pharmacodynamic modeling results
  • Regular monitoring of drug pharmacokinetic-pharmacodynamic interactions results
  • Regular monitoring of drug pharmacokin
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12 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Autoimmune polyglandular failure - Prevention

Autoimmune polyglandular failure can be prevented by avoiding long-term exposure to environmental toxins, maintaining a healthy lifestyle, and getting regular check-ups to monitor hormone levels. additionally, if someone has a family history of autoimmune diseases, they should be more vigilant in monitoring their health and seeking medical advice if they experience any symptoms.