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(E76.1) Mucopolysaccharidosis, type ii
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53 490 in individuals diagnosis mucopolysaccharidosis, type ii confirmed
3 431 deaths with diagnosis mucopolysaccharidosis, type ii
6% mortality rate associated with the disease mucopolysaccharidosis, type ii
Diagnosis mucopolysaccharidosis, type ii is diagnosed Men are 67.58% more likely than Women
44 819
Men receive the diagnosis mucopolysaccharidosis, type ii
1 962 (4.4 %)Died from this diagnosis.
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8 671
Women receive the diagnosis mucopolysaccharidosis, type ii
1 469 (16.9 %)Died from this diagnosis.
Risk Group for the Disease mucopolysaccharidosis, type ii - Men aged 15-19 and Women aged 10-14
In Men diagnosis is most often set at age 0-34, 45-49, 60-64
Less common in men the disease occurs at Age 35-44, 50-59, 65-95+Less common in women the disease occurs at Age 0-1, 20-34, 40-49, 55-79, 85-95+
In Women diagnosis is most often set at age 0-19, 35-39, 50-54, 80-84
Disease Features mucopolysaccharidosis, type ii
Absence or low individual and public risk
Mucopolysaccharidosis, type ii - what does this mean
Mucopolysaccharidosis, type ii, is a genetic disorder caused by a deficiency of the enzyme iduronate-2-sulfatase, which results in the accumulation of glycosaminoglycans in the body's cells and tissues. this accumulation leads to progressive physical and mental deterioration, and can result in a wide range of symptoms, including skeletal deformities, hearing loss, vision problems, enlarged liver and spleen, and heart and respiratory problems.
What happens during the disease - mucopolysaccharidosis, type ii
Mucopolysaccharidosis type ii (mps ii) is an inherited lysosomal storage disorder caused by a deficiency in the enzyme iduronate-2-sulfatase. this enzyme is responsible for the breakdown of glycosaminoglycans, which are complex carbohydrates found in the lysosomes of cells. without the enzyme, glycosaminoglycans accumulate in the lysosomes of cells, leading to progressive damage to the organs and tissues, including the heart, lungs, skeleton, and central nervous system.
Clinical Pattern
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How does a doctor diagnose
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Treatment and Medical Assistance
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9 Days of Hospitalization Required
303 Hours Required for Outpatient Treatment
Mucopolysaccharidosis, type ii - Prevention
The best way to prevent mucopolysaccharidosis, type ii is through prenatal screening and genetic counseling. couples who are considering having a child should be informed about the risk of this condition and the availability of genetic testing. if the parents are found to be carriers, prenatal testing can be done to determine if the fetus is affected.