Central pontine myelinolysis - what does this mean
Central pontine myelinolysis is a neurological disorder caused by rapid correction of sodium levels in the body, which leads to damage of the myelin sheath of nerve fibers in the brain stem. this damage results in a wide range of neurological symptoms, including paralysis, difficulty speaking and swallowing, and changes in mental status.
What happens during the disease - central pontine myelinolysis
Central pontine myelinolysis is a neurological disorder caused by a rapid decrease in the osmolality of the extracellular fluid, leading to an influx of water into the cells. this causes an imbalance of electrolytes, resulting in the swelling and destruction of the myelin sheath, which is a protective layer around nerve cells. this leads to the disruption of nerve conduction and the clinical manifestation of the disease.
Central pontine myelinolysis - Prevention
Central pontine myelinolysis can be prevented by avoiding rapid correction of electrolyte imbalances, such as hyponatremia, especially in those with chronic alcohol abuse or malnutrition. additionally, it is important to ensure that patients are adequately hydrated before initiating osmotic diuresis.