(A50.4) Late congenital neurosyphilis [juvenile neurosyphilis]

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10 407 in individuals diagnosis late congenital neurosyphilis [juvenile neurosyphilis] confirmed
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3 310 deaths with diagnosis late congenital neurosyphilis [juvenile neurosyphilis]
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32% mortality rate associated with the disease late congenital neurosyphilis [juvenile neurosyphilis]

Diagnosis late congenital neurosyphilis [juvenile neurosyphilis] is diagnosed Women are 7.08% more likely than Men

4 835

Men receive the diagnosis late congenital neurosyphilis [juvenile neurosyphilis]

2 803 (58.0 %)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
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35
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15
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5
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5 572

Women receive the diagnosis late congenital neurosyphilis [juvenile neurosyphilis]

507 (9.1 %)

Died from this diagnosis.

Risk Group for the Disease late congenital neurosyphilis [juvenile neurosyphilis] - Men and Women aged 0

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In Men diagnosis is most often set at age 0-5, 10-14, 30-34, 45-49, 60-79
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Less common in men the disease occurs at Age 5-9, 15-29, 35-44, 50-59, 80-95+Less common in women the disease occurs at Age 0-24, 45-69, 80-84, 90-95+
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In Women diagnosis is most often set at age 0-1, 25-44, 70-79, 85-89

Disease Features late congenital neurosyphilis [juvenile neurosyphilis]

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Absence or low individual and public risk
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Late congenital neurosyphilis [juvenile neurosyphilis] - what does this mean

Late congenital neurosyphilis (juvenile neurosyphilis) is a rare form of neurosyphilis that occurs when a mother passes the infection to her child in utero. it is caused by the bacterium treponema pallidum, which is transmitted through sexual contact or from mother to infant during the birth process. it can cause a wide range of neurological and psychiatric symptoms, including seizures, cognitive impairment, personality changes, and psychosis.

What happens during the disease - late congenital neurosyphilis [juvenile neurosyphilis]

Late congenital neurosyphilis (juvenile neurosyphilis) is a rare form of neurosyphilis that is caused by the transmission of treponema pallidum from an infected mother to her fetus. it is characterized by the inflammation of the central nervous system, which can cause various neurological symptoms, such as seizures, changes in mental state, and hearing and vision disturbances. this inflammation is caused by the body's immune response to the bacteria, resulting in the destruction of the myelin sheath that surrounds the nerves. if left untreated, it can lead to permanent neurological damage and even death.

Clinical Pattern

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How does a doctor diagnose

  • Physical examination to detect signs of the disease
  • Laboratory tests to look for antibodies to the bacteria that cause syphilis
  • Blood tests to measure levels of certain antibodies and proteins
  • Imaging tests such as MRI or CT scan to look for signs of brain damage
  • Lumbar puncture to collect cerebrospinal fluid for analysis
  • Electroencephalogram (EEG) to measure electrical activity in the brain
  • Neuropsychological tests to assess mental and cognitive abilities
  • Additional tests to rule out other conditions

Treatment and Medical Assistance

Main goal of the treatment: To reduce the symptoms of late congenital neurosyphilis and prevent further complications.
  • Prescribe appropriate antibiotics to treat the infection.
  • Administer medications to reduce inflammation.
  • Monitor the patient's neurological and physical development.
  • Provide physical therapy to help the patient regain strength and mobility.
  • Provide psychological support and counseling to help the patient cope with the effects of the disease.
  • Educate the patient and their family about the disease and its treatment.
  • Perform regular follow-up visits to monitor the patient's progress.
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30 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Late congenital neurosyphilis [juvenile neurosyphilis] - Prevention

The best way to prevent late congenital neurosyphilis (juvenile neurosyphilis) is through the screening of pregnant women for syphilis and the treatment of those who are positive. additionally, practicing safe sex and avoiding contact with individuals who have syphilis can help reduce the risk of infection.