(G82.1) Spastic paraplegia

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2 323 425 in individuals diagnosis spastic paraplegia confirmed

27 282 deaths with diagnosis spastic paraplegia

1% mortality rate associated with the disease spastic paraplegia

Etiology Pathogenesis Clinical Pattern Diagnostics Treatment Prevention

Diagnosis spastic paraplegia is diagnosed Men are 20.09% more likely than Women

1 395 127

Men receive the diagnosis spastic paraplegia

15 785 (1.1 %)

Died from this diagnosis.

100

928 298

Women receive the diagnosis spastic paraplegia

11 497 (1.2 %)

Died from this diagnosis.

Risk Group for the Disease spastic paraplegia - Men aged 55-59 and Women aged 60-64

In Men diagnosis is most often set at age 0-94

Less common in men the disease occurs at Age 95+in in women, the disease manifests at any age

In Women diagnosis is most often set at age 0-95+

Disease Features spastic paraplegia

Absence or low individual and public risk

Spastic paraplegia - what does this mean

Spastic paraplegia is a type of motor neuron disease that causes progressive weakness and stiffness in the muscles of the legs due to damage to the upper motor neurons in the brain and spinal cord. this damage leads to an increase in muscle tone and spasms, leading to difficulty walking and maintaining balance.

What happens during the disease - spastic paraplegia

Spastic paraplegia is a neurological disorder that is caused by damage to the upper motor neurons in the spinal cord. this damage can be caused by a variety of genetic, environmental, or acquired factors, such as trauma, infection, or autoimmune diseases. the damage to the upper motor neurons leads to an imbalance in the excitatory and inhibitory signals to the lower motor neurons, resulting in spasticity and paralysis of the legs. this can cause difficulty with walking, balance, and coordination, as well as muscle weakness and spasms.

Clinical Pattern

More details coming soon

How does a doctor diagnose

Clinical evaluation and medical history
Neurological examination
Genetic testing
MRI scan
Electromyography (EMG)
Nerve conduction velocity (NCV) study
Cerebrospinal fluid (CSF) analysis
Brainstem auditory evoked potentials (BAEPs)

Treatment and Medical Assistance

Main goal of the treatment: To reduce the severity of the symptoms of spastic paraplegia.

Physical therapy
Occupational therapy
Stretching exercises
Strengthening exercises
Balance exercises
Posture correction exercises
Assistive devices such as canes and walkers
Medication to reduce spasticity
Surgery to correct any underlying issues

52 Days of Hospitalization Required

Average Time for Outpatient Care Not Established

Spastic paraplegia - Prevention

The best way to prevent spastic paraplegia is to maintain a healthy lifestyle, including regular exercise, eating a balanced diet, avoiding smoking and alcohol, and managing stress. additionally, it is important to get regular check-ups with your doctor to ensure that any underlying medical conditions that may contribute to the development of spastic paraplegia are identified and treated promptly.

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