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(H49.4) Progressive external ophthalmoplegia
More details coming soon
126 524 in individuals diagnosis progressive external ophthalmoplegia confirmed
2 543 deaths with diagnosis progressive external ophthalmoplegia
2% mortality rate associated with the disease progressive external ophthalmoplegia
Diagnosis progressive external ophthalmoplegia is diagnosed Men are 6.32% more likely than Women
67 257
Men receive the diagnosis progressive external ophthalmoplegia
681 (1.0 %)Died from this diagnosis.
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59 267
Women receive the diagnosis progressive external ophthalmoplegia
1 862 (3.1 %)Died from this diagnosis.
Risk Group for the Disease progressive external ophthalmoplegia - Men and Women aged 55-59
In Men diagnosis is most often set at age 0-95+
Less common in men the disease occurs at Age 0-1Less common in women the disease occurs at Age 95+
In Women diagnosis is most often set at age 0-94
Disease Features progressive external ophthalmoplegia
Absence or low individual and public risk
Progressive external ophthalmoplegia - what does this mean
Progressive external ophthalmoplegia is a rare genetic disorder caused by mutations in mitochondrial dna, resulting in a decrease in the function of the muscles that control eye movement. symptoms usually begin in the teenage years and include droopy eyelids, double vision, and difficulty moving the eyes in all directions. over time, the condition can lead to complete paralysis of the eye muscles, resulting in a complete inability to move the eyes.
What happens during the disease - progressive external ophthalmoplegia
Progressive external ophthalmoplegia (peo) is a rare disorder caused by mutations in the mitochondrial dna, leading to an impaired ability of the mitochondria to produce energy. this results in a decrease in the amount of atp available for the muscles of the eye, leading to progressive weakness of the muscles surrounding the eye, and resulting in difficulty in moving the eye.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Detailed medical history
- Physical examination
- Neurological examination
- Eye examination
- Genetic testing
- Brain MRI
- Electromyography
- Nerve conduction studies
- Blood tests
- Urine tests
Treatment and Medical Assistance
Main Goal: To reduce the symptoms of Progressive External Ophthalmoplegia
- Regular physical exercise and stretching
- Regular eye exercises
- Medications to reduce muscle weakness
- Intravenous immunoglobulin (IVIG) therapy
- Plasmapheresis
- Surgery to repair muscle damage
- Vitamin E supplementation
- Coenzyme Q10 supplementation
- Speech therapy
- Occupational therapy
- Nutritional counseling
8 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Progressive external ophthalmoplegia - Prevention
Progressive external ophthalmoplegia can be prevented by early diagnosis and treatment of underlying causes, such as mitochondrial diseases, hormone deficiencies, or thyroid problems. it is also important to maintain a healthy lifestyle and diet rich in antioxidants, as well as avoiding excessive exposure to ultraviolet radiation.