(D71) Functional disorders of polymorphonuclear neutrophils

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18 345 in individuals diagnosis functional disorders of polymorphonuclear neutrophils confirmed
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3 083 deaths with diagnosis functional disorders of polymorphonuclear neutrophils
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17% mortality rate associated with the disease functional disorders of polymorphonuclear neutrophils

Diagnosis functional disorders of polymorphonuclear neutrophils is diagnosed Men are 32.80% more likely than Women

12 181

Men receive the diagnosis functional disorders of polymorphonuclear neutrophils

1 699 (13.9 %)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
6 164

Women receive the diagnosis functional disorders of polymorphonuclear neutrophils

1 384 (22.5 %)

Died from this diagnosis.

Risk Group for the Disease functional disorders of polymorphonuclear neutrophils - Men aged 10-14 and Women aged 0-5

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In Men diagnosis is most often set at age 0-24, 40-44, 50-54, 60-79
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Less common in men the disease occurs at Age 25-39, 45-49, 55-59, 80-95+Less common in women the disease occurs at Age 10-19, 30-34, 45-54, 85-95+
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In Women diagnosis is most often set at age 0-9, 20-29, 35-44, 55-84

Disease Features functional disorders of polymorphonuclear neutrophils

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Absence or low individual and public risk
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Functional disorders of polymorphonuclear neutrophils - what does this mean

Functional disorders of polymorphonuclear neutrophils (pmns) occur when the pmns are unable to perform their normal functions, such as phagocytosis, chemotaxis, and release of enzymes and lysosomes. this can be caused by genetic or acquired conditions, including autoimmune diseases, infections, and certain drugs.

What happens during the disease - functional disorders of polymorphonuclear neutrophils

Functional disorders of polymorphonuclear neutrophils (pmns) are caused by a variety of factors, including genetic defects, immune-mediated mechanisms, infections, and environmental exposures. these disorders can result in decreased production of pmns, decreased activity of pmns, or increased clearance of pmns from the circulation. this can lead to a wide range of clinical symptoms, including increased susceptibility to infection, increased inflammation, and impaired wound healing.

Clinical Pattern

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How does a doctor diagnose

  • Complete Blood Count (CBC)
  • Bone Marrow Biopsy
  • Flow Cytometry
  • Immunophenotyping
  • Cytochemistry
  • Cytogenetic Analysis
  • Molecular Genetic Testing
  • Peripheral Blood Smear
Additional measures:
  • X-Ray
  • CT Scan
  • MRI Scan

Treatment and Medical Assistance

Main goal of the treatment: To improve the function of polymorphonuclear neutrophils.
  • Prescribing antibiotics to reduce bacterial infection
  • Prescribing corticosteroids to reduce inflammation
  • Administering intravenous immunoglobulin to improve neutrophil function
  • Administering hematopoietic stem cell transplantation to restore normal neutrophil function
  • Prescribing immunomodulatory drugs to reduce inflammation
  • Providing nutritional support to improve neutrophil function
  • Administering immunoglobulin replacement therapy to improve neutrophil function
  • Administering chemotherapy to reduce the number of abnormal neutrophils
  • Providing supportive care to reduce the severity of symptoms
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27 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Functional disorders of polymorphonuclear neutrophils - Prevention

Functional disorders of polymorphonuclear neutrophils can be prevented by maintaining a healthy lifestyle, exercising regularly, eating a balanced diet, avoiding smoking, and getting regular medical check-ups. additionally, vaccinations can help prevent certain infections that can lead to functional disorders of polymorphonuclear neutrophils.

Specified forms of the disease

(I06.0) Rheumatic aortic stenosis
(I06.1) Rheumatic aortic insufficiency
(I06.2) Rheumatic aortic stenosis with insufficiency
(I06.8) Other rheumatic aortic valve diseases
(I06.9) Rheumatic aortic valve disease, unspecified