Kyphoscoliotic heart disease - what does this mean
Kyphoscoliotic heart disease is a rare congenital disorder in which the heart is abnormally shaped and connected to the chest wall, resulting in a restricted flow of blood to and from the heart. it is caused by a genetic mutation that affects the development of connective tissue in the body, leading to an abnormal curvature of the spine and chest wall.
What happens during the disease - kyphoscoliotic heart disease
Kyphoscoliotic heart disease is a rare congenital disorder caused by mutations in the gene encoding the connective tissue protein fibrillin-1. this mutation leads to a decrease in the production of the protein, causing a decrease in the elasticity of the aortic wall. this decrease in elasticity leads to an increase in the pressure of the aorta, which can cause aortic dilation and aneurysm formation. over time, this can lead to a weakening of the walls of the heart chambers, leading to a decrease in cardiac output and an increased risk of heart failure.
Kyphoscoliotic heart disease - Prevention
Kyphoscoliotic heart disease can be prevented through lifestyle modifications such as maintaining a healthy diet, exercising regularly, and avoiding smoking and excessive alcohol consumption. additionally, regular screening for cardiovascular risk factors such as high cholesterol, high blood pressure, and diabetes can help to identify those at risk of developing this condition and allow for early intervention.