(K74.4) Secondary biliary cirrhosis

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3 178 376 in individuals diagnosis secondary biliary cirrhosis confirmed
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604 335 deaths with diagnosis secondary biliary cirrhosis
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19% mortality rate associated with the disease secondary biliary cirrhosis

Diagnosis secondary biliary cirrhosis is diagnosed Men are 16.39% more likely than Women

1 849 579

Men receive the diagnosis secondary biliary cirrhosis

391 524 (21.2 %)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
1 328 797

Women receive the diagnosis secondary biliary cirrhosis

212 811 (16.0 %)

Died from this diagnosis.

Risk Group for the Disease secondary biliary cirrhosis - Men and Women aged 55-59

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In Men diagnosis is most often set at age 0-95+
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in in men, the disease manifests at any agein in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features secondary biliary cirrhosis

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Absence or low individual and public risk
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Secondary biliary cirrhosis - what does this mean

Secondary biliary cirrhosis is a liver disease caused by long-term obstruction of the bile ducts, which can be due to a variety of conditions, such as primary biliary cirrhosis, primary sclerosing cholangitis, gallstones, or tumors. this obstruction leads to a build-up of bile in the liver, leading to inflammation and scarring of the liver tissue, ultimately resulting in cirrhosis.

What happens during the disease - secondary biliary cirrhosis

Secondary biliary cirrhosis is a progressive condition caused by long-term obstruction of the bile ducts. this obstruction can be caused by a variety of conditions, such as primary biliary cholangitis, primary sclerosing cholangitis, benign biliary strictures, and choledochal cysts. the obstruction of the bile ducts leads to impaired bile flow, which leads to inflammation and fibrosis of the bile ducts. the inflammation and fibrosis can eventually lead to scarring of the bile ducts, which can lead to further obstruction and eventually to cirrhosis.

Clinical Pattern

More details coming soon

How does a doctor diagnose

  • Physical examination
  • Blood tests for liver function
  • Ultrasound scan
  • Magnetic resonance imaging (MRI) scan
  • Liver biopsy
  • Endoscopic retrograde cholangiopancreatography (ERCP)
Additions:
  • Abdominal CT scan
  • Liver function tests

Treatment and Medical Assistance

Main goal of the treatment: Treat the underlying cause of secondary biliary cirrhosis and reduce the risk of complications.
  • Treatment of the underlying cause (e.g. stopping alcohol consumption, treating infections, etc.)
  • Liver transplantation if indicated
  • Medications to reduce symptoms and complications (e.g. diuretics, antibiotics, antifungals, antivirals, etc.)
  • Nutritional supplements and a balanced diet
  • Regular monitoring of liver function tests
  • Avoidance of hepatotoxic medications and substances
  • Regular exercise and physical activity
  • Regular monitoring of blood pressure
  • Avoidance of excessive alcohol consumption
  • Regular monitoring of blood glucose levels
  • Vaccinations to prevent infections
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19 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Secondary biliary cirrhosis - Prevention

Secondary biliary cirrhosis can be prevented by avoiding alcohol consumption, maintaining a healthy diet, and avoiding the use of certain medications such as methotrexate, sulfasalazine, and nitrofurantoin. additionally, regular check-ups with a doctor can help to identify any potential issues early on.