Drug-induced pemphigus - what does this mean
Drug-induced pemphigus is an autoimmune disorder that occurs when a person takes a medication that triggers an immune system response causing the body to produce antibodies that attack healthy skin cells, leading to painful blisters and open sores on the skin and mucous membranes.
What happens during the disease - drug-induced pemphigus
Drug-induced pemphigus is an autoimmune disorder triggered by certain medications, such as antibiotics, anticonvulsants, and non-steroidal anti-inflammatory drugs. the drugs trigger the production of autoantibodies which attack and destroy the desmosomes, a type of cell junction, in the skin and mucous membranes. this leads to the formation of blisters and erosions in the affected areas.
Treatment and Medical Assistance
Main goal of the treatment: To reduce the severity of symptoms and reduce the risk of complications.
- Prescribing medications to reduce inflammation and suppress the immune system.
- Providing topical and/or systemic corticosteroids.
- Prescribing immunosuppressants to reduce the activity of the immune system.
- Prescribing antibiotics to treat bacterial infections.
- Prescribing antivirals to treat viral infections.
- Providing topical and/or systemic antifungal medications to treat fungal infections.
- Providing topical and/or systemic antihistamines to reduce itching.
- Providing topical and/or systemic moisturizers to reduce dryness.
- Providing phototherapy to reduce inflammation.
- Providing physical therapy to reduce pain and improve mobility.
- Providing lifestyle advice to reduce stress and improve overall health.
15 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Drug-induced pemphigus - Prevention
Drug-induced pemphigus can be prevented by avoiding the use of medications that are known to trigger the disease, such as certain antibiotics, anti-convulsants, and diuretics. additionally, it is important to consult with a physician before beginning any new medication, and to be aware of any potential side effects.