DocSym
β
Searchsearch
Search
(L12.3) Acquired epidermolysis bullosa
More details coming soon
231 237 in individuals diagnosis acquired epidermolysis bullosa confirmed
8 706 deaths with diagnosis acquired epidermolysis bullosa
4% mortality rate associated with the disease acquired epidermolysis bullosa
Diagnosis acquired epidermolysis bullosa is diagnosed Women are 18.79% more likely than Men
93 894
Men receive the diagnosis acquired epidermolysis bullosa
3 346 (3.6 %)Died from this diagnosis.
100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
137 343
Women receive the diagnosis acquired epidermolysis bullosa
5 360 (3.9 %)Died from this diagnosis.
Risk Group for the Disease acquired epidermolysis bullosa - Men and Women aged 80-84
In Men diagnosis is most often set at age 0-14, 25-95+
Less common in men the disease occurs at Age 15-24in in women, the disease manifests at any age
In Women diagnosis is most often set at age 0-95+
Disease Features acquired epidermolysis bullosa
Absence or low individual and public risk
Acquired epidermolysis bullosa - what does this mean
Acquired epidermolysis bullosa is a rare, inherited skin disorder characterized by recurrent blister formation caused by minor trauma to the skin. it is caused by a defect in the proteins responsible for connecting the outer layer of the skin (epidermis) to the inner layer (dermis). this results in the formation of blisters and erosions on the skin, which can cause pain and scarring.
What happens during the disease - acquired epidermolysis bullosa
Acquired epidermolysis bullosa is a rare, inherited skin disorder caused by mutations in the genes responsible for producing proteins that form the anchoring filaments which attach the epidermis to the dermis. this results in weakened skin and the formation of blisters and erosions, especially in areas of friction or trauma. the disorder is characterized by recurrent, painful, and fragile blisters, erosions, and scarring of the skin and mucous membranes.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Physical examination of the skin
- Biopsy of the affected skin
- Blood test to check for antibodies to type VII collagen
- Molecular genetic testing to detect mutations in the COL7A1 gene
- Electron microscopy to observe the structure of the skin
- Immunofluorescence to detect the presence of type VII collagen
- Skin culture to detect the presence of certain bacteria
Treatment and Medical Assistance
Main goal of the treatment: To reduce the symptoms of Acquired Epidermolysis Bullosa and improve the patient's quality of life.
- Provide wound care, such as cleaning, bandaging, and moisturizing.
- Prescribe medications such as antibiotics, anti-inflammatory drugs, and pain relievers.
- Perform skin grafts and other surgical procedures to repair damaged skin.
- Administer injections of growth factors to stimulate healing.
- Provide nutritional counseling to ensure the patient is getting adequate nutrition.
- Recommend physical therapy and other rehabilitative treatments to maintain mobility and reduce pain.
- Provide psychological counseling to help the patient cope with the condition.
22 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Acquired epidermolysis bullosa - Prevention
The best way to prevent acquired epidermolysis bullosa is to practice good hygiene and avoid contact with people who may have the condition. it is also important to be aware of any family history of the condition, and to take steps to reduce the risk of infection, such as regular hand-washing and avoiding contact with people who may have the condition. vaccinations and regular check-ups with a doctor can also help to reduce the risk of developing the condition.