(L51.0) Nonbullous erythema multiforme

Nonbullous erythema multiforme is an acute skin condition characterized by symmetrical, red-purple lesions that typically appear on the hands and feet and can spread to other parts of the body. it is believed to be caused by an immune reaction to an infection or medication, although the exact cause is unknown.

Nonbullous erythema multiforme is an autoimmune disorder that is caused by an abnormal immune response to certain medications, infections, or other triggers. it is characterized by the formation of red, raised patches on the skin that can be itchy or painful. these patches are usually symmetrical and form in a target-like shape. the underlying cause of the disorder is thought to be an abnormal immune response to an antigen, resulting in the activation of immune cells and the release of inflammatory mediators that cause tissue damage and skin lesions.

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• Physical exam to assess the size, shape and location of skin lesions
• Skin biopsy to confirm the diagnosis
• Blood tests to check for infection and inflammation
• Urine tests to check for infection
• CT scan to check for any underlying organ involvement
• X-ray to check for any bone involvement
• Allergy testing to determine if the condition is caused by an allergic reaction

Additional measures (if necessary):

• MRI to check for any neurological involvement
• Tumor marker tests to check for any underlying cancer

Main goal of the treatment: To reduce inflammation and prevent recurrence of Nonbullous Erythema Multiforme.

• Prescribe topical steroids to reduce inflammation.
• Prescribe oral antihistamines to reduce itching and discomfort.
• Prescribe systemic corticosteroids to reduce inflammation.
• Prescribe topical immunomodulators to reduce inflammation.
• Prescribe oral antibiotics to reduce infection.
• Prescribe photoprotective measures to reduce UV exposure.
• Prescribe topical calcineurin inhibitors to reduce inflammation.
• Prescribe topical retinoids to reduce inflammation.
• Prescribe topical antiseptics to reduce infection.
• Prescribe topical emollients to reduce itching and discomfort.
• Prescribe topical moisturizers to reduce dryness.
• Prescribe topical keratolytics to reduce scaling.

Nonbullous erythema multiforme can be prevented by avoiding known triggers such as certain medications, infections, and allergies. additionally, it is important to practice good skin care, including avoiding excessive sun exposure and using sunscreen when outdoors.