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(M31.1) Thrombotic microangiopathy
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861 581 in individuals diagnosis thrombotic microangiopathy confirmed
31 991 deaths with diagnosis thrombotic microangiopathy
4% mortality rate associated with the disease thrombotic microangiopathy
Diagnosis thrombotic microangiopathy is diagnosed Women are 11.89% more likely than Men
379 577
Men receive the diagnosis thrombotic microangiopathy
17 557 (4.6 %)Died from this diagnosis.
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482 004
Women receive the diagnosis thrombotic microangiopathy
14 434 (3.0 %)Died from this diagnosis.
Risk Group for the Disease thrombotic microangiopathy - Men and Women aged 55-59
In Men diagnosis is most often set at age 0-94
Less common in men the disease occurs at Age 95+in in women, the disease manifests at any age
In Women diagnosis is most often set at age 0-95+
Disease Features thrombotic microangiopathy
Absence or low individual and public risk
Thrombotic microangiopathy - what does this mean
Thrombotic microangiopathy is a condition where the small blood vessels become blocked due to the formation of small blood clots, leading to damage of the blood vessels and organ damage. this is caused by an imbalance in the clotting system, leading to an increased risk of clotting and decreased ability to break down clots.
What happens during the disease - thrombotic microangiopathy
Thrombotic microangiopathy is a disorder characterized by the formation of small blood clots in the small blood vessels of the body. this is usually caused by a defect in the platelet activation process, resulting in an increase in the number of activated platelets that form a clot. additionally, damage to the endothelial cells of the small blood vessels can lead to an increased production of pro-coagulant factors, further exacerbating the clotting process. this can result in organ damage and decreased organ function.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete medical history and physical examination
- Complete blood count (CBC) and peripheral smear
- Serum electrolytes and creatinine
- Liver function tests
- Coagulation studies
- Urinalysis
- Renal biopsy
- Computed tomography (CT) scan or Magnetic Resonance Imaging (MRI) of the abdomen
- Kidney ultrasound
- Thrombophilia panel
- Vitamin B12 and folate levels
- Serum protein electrophoresis and immunofixation
- Antinuclear antibody (ANA) and anti-neutrophil cytoplasmic antibody (ANCA) tests
- Testing for complement levels
- Testing for antiphospholipid antibodies
- Testing for factor H autoantibodies
Treatment and Medical Assistance
Main goal of the treatment: To reduce the risk of thrombotic microangiopathy and its symptoms.
- Prescribe anticoagulants and antiplatelet agents to reduce the risk of thrombosis.
- Prescribe corticosteroids to reduce inflammation.
- Prescribe immunosuppressants to reduce the activity of the immune system.
- Prescribe diuretics to reduce fluid buildup.
- Prescribe medications to treat high blood pressure.
- Prescribe medications to treat abnormal blood clotting.
- Prescribe medications to treat anemia.
- Prescribe medications to treat kidney failure.
- Prescribe antibiotics to treat infections.
- Perform regular blood tests to monitor clotting factors.
- Perform regular ultrasounds to monitor any changes in the arteries.
- Perform regular kidney function tests to monitor kidney function.
- Perform regular liver function tests to monitor liver function.
- Encourage a healthy lifestyle with regular exercise and a balanced diet.
16 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Thrombotic microangiopathy - Prevention
Thrombotic microangiopathy is best prevented by maintaining a healthy lifestyle, such as eating a balanced diet, exercising regularly, and avoiding smoking and excessive alcohol consumption. additionally, it is important to monitor and control any existing chronic conditions, such as diabetes, hypertension, and obesity, as these can increase the risk of developing thrombotic microangiopathy.