(M80.1) Postoophorectomy osteoporosis with pathological fracture

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1 643 865 in individuals diagnosis postoophorectomy osteoporosis with pathological fracture confirmed
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39 170 deaths with diagnosis postoophorectomy osteoporosis with pathological fracture
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2% mortality rate associated with the disease postoophorectomy osteoporosis with pathological fracture

Diagnosis postoophorectomy osteoporosis with pathological fracture is diagnosed Women are 68.17% more likely than Men

261 629

Men receive the diagnosis postoophorectomy osteoporosis with pathological fracture

13 318 (5.1 %)

Died from this diagnosis.

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1 382 236

Women receive the diagnosis postoophorectomy osteoporosis with pathological fracture

25 852 (1.9 %)

Died from this diagnosis.

Risk Group for the Disease postoophorectomy osteoporosis with pathological fracture - Men and Women aged 80-84

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In Men diagnosis is most often set at age 0-19, 25-95+
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Less common in men the disease occurs at Age 20-24in in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features postoophorectomy osteoporosis with pathological fracture

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Absence or low individual and public risk
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Postoophorectomy osteoporosis with pathological fracture - what does this mean

Postoophorectomy osteoporosis with pathological fracture occurs when a woman has had her ovaries removed (postoophorectomy) and develops decreased bone mineral density (osteoporosis) due to the decreased levels of estrogen. this can lead to a weakened bone structure and an increased likelihood of fracture, even with minimal trauma (pathological fracture).

What happens during the disease - postoophorectomy osteoporosis with pathological fracture

Postoophorectomy osteoporosis with pathological fracture is caused by the loss of the hormone estrogen, which is produced by the ovaries and is important for maintaining bone density. without the presence of estrogen, the bones become weak and brittle, leading to an increased risk of fractures, especially in the spine and hips. the pathological fracture occurs when a bone breaks due to the weakened state of the bone, and is often the result of a minor trauma or fall.

Clinical Pattern

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How does a doctor diagnose

  • Complete physical exam
  • Blood tests (calcium, vitamin D, phosphorus, parathyroid hormone, alkaline phosphatase)
  • Bone density test (DEXA scan)
  • X-ray of affected area
  • CT scan of affected area
  • MRI of affected area
  • Biochemical markers of bone turnover
  • Bone biopsy

Treatment and Medical Assistance

Main goal of the treatment: To reduce the risk of further fractures and to improve bone quality.
  • Prescription of calcium and vitamin D supplements
  • Weight-bearing exercises
  • Hormone replacement therapy
  • Bisphosphonate medications
  • Calcitonin injections
  • Denosumab injections
  • Strontium Ranelate medications
  • Parathyroid hormone injections
  • Physical therapy
  • Surgery (postoophorectomy)
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23 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Postoophorectomy osteoporosis with pathological fracture - Prevention

Postoophorectomy osteoporosis with pathological fracture can be prevented by maintaining an adequate calcium and vitamin d intake, exercising regularly, and avoiding smoking and excessive alcohol consumption. additionally, it is important to have regular bone density scans to detect any changes in bone density early, and to discuss any medications and treatments with a doctor.