(M80.4) Drug-induced osteoporosis with pathological fracture

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1 643 865 in individuals diagnosis drug-induced osteoporosis with pathological fracture confirmed
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39 170 deaths with diagnosis drug-induced osteoporosis with pathological fracture
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2% mortality rate associated with the disease drug-induced osteoporosis with pathological fracture

Diagnosis drug-induced osteoporosis with pathological fracture is diagnosed Women are 68.17% more likely than Men

261 629

Men receive the diagnosis drug-induced osteoporosis with pathological fracture

13 318 (5.1 %)

Died from this diagnosis.

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1 382 236

Women receive the diagnosis drug-induced osteoporosis with pathological fracture

25 852 (1.9 %)

Died from this diagnosis.

Risk Group for the Disease drug-induced osteoporosis with pathological fracture - Men and Women aged 80-84

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In Men diagnosis is most often set at age 0-19, 25-95+
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Less common in men the disease occurs at Age 20-24in in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features drug-induced osteoporosis with pathological fracture

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Absence or low individual and public risk
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Drug-induced osteoporosis with pathological fracture - what does this mean

Drug-induced osteoporosis with pathological fracture occurs when the use of certain prescription medications, such as glucocorticoids, leads to a decrease in bone mineral density which weakens the bones and increases the risk of fracture. the pathological fracture is a fracture that occurs due to the weakened bone structure, and is typically more severe than a normal fracture.

What happens during the disease - drug-induced osteoporosis with pathological fracture

Drug-induced osteoporosis with pathological fracture is a condition in which long-term use of certain medications, such as corticosteroids, anticonvulsants, and some chemotherapeutic agents, leads to a decrease in bone density and an increased risk of fracture. this decrease in bone density can lead to a weakened bone structure, making it more vulnerable to fractures, even from minor trauma. additionally, the decrease in bone density can cause a decrease in bone strength, leading to an increased risk of spontaneous fractures.

Clinical Pattern

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How does a doctor diagnose

  • Complete medical history and physical examination
  • Blood tests to check calcium, phosphorus, and alkaline phosphatase levels
  • Bone density scan (DXA)
  • X-rays of the affected area
  • CT scan or MRI of the affected area
  • Bone biopsy
  • Kidney function tests
  • Thyroid function tests

Treatment and Medical Assistance

Main goal of the treatment: To reduce the risk of further fractures and improve bone density.
  • Prescribe medications to reduce bone breakdown and increase bone mineral density.
  • Administer calcium, vitamin D and other supplements to enhance bone health.
  • Provide lifestyle counseling to increase physical activity and reduce risk factors such as smoking.
  • Perform imaging studies to assess bone density and detect fractures.
  • Refer to physical therapy for exercises to strengthen bones.
  • Refer to a specialist for further evaluation and management.
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23 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Drug-induced osteoporosis with pathological fracture - Prevention

The best way to prevent drug-induced osteoporosis with pathological fracture is to practice healthy lifestyle habits such as eating a balanced diet, exercising regularly, and avoiding smoking and excessive alcohol consumption. additionally, taking medications that are known to increase the risk of osteoporosis should be done under the guidance of a healthcare provider.