DocSym
β
Searchsearch
Search
(M88.0) Paget disease of skull
More details coming soon
26 934 in individuals diagnosis paget disease of skull confirmed
5 672 deaths with diagnosis paget disease of skull
21% mortality rate associated with the disease paget disease of skull
Diagnosis paget disease of skull is diagnosed Women are 31.03% more likely than Men
9 288
Men receive the diagnosis paget disease of skull
2 244 (24.2 %)Died from this diagnosis.
100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
17 646
Women receive the diagnosis paget disease of skull
3 428 (19.4 %)Died from this diagnosis.
Risk Group for the Disease paget disease of skull - Men aged 55-59 and Women aged 50-54
In Men diagnosis is most often set at age 0-14, 25-29, 40-89
Less common in men the disease occurs at Age 0-1, 15-24, 30-39, 90-95+Less common in women the disease occurs at Age 0-19, 40-44, 90-95+
In Women diagnosis is most often set at age 20-39, 45-89
Disease Features paget disease of skull
Absence or low individual and public risk
Paget disease of skull - what does this mean
Paget disease of the skull is a chronic bone disorder caused by an abnormal increase in the rate of bone remodeling. this leads to the formation of abnormal bone with a disorganized structure, which can cause skull deformities, cranial nerve compression, hearing loss, and pain.
What happens during the disease - paget disease of skull
Paget disease of the skull is a disorder of bone remodeling caused by abnormal activity of osteoclasts and osteoblasts. osteoclasts become overactive, leading to increased bone resorption and weakened bone structure. osteoblasts become underactive, leading to decreased bone formation and a thickening of the affected bone. the combination of these two processes results in a disorganized and weakened bone structure that can cause deformities of the skull, facial bones, and other bones in the body.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Clinical history and physical examination
- CT scan of the skull
- MRI of the skull
- Biochemical markers
- Bone scan
- X-ray of the skull
Treatment and Medical Assistance
Main goal of the treatment: To reduce bone pain and deformity, and to prevent complications.
- Medications to reduce bone turnover and pain, such as bisphosphonates
- Surgery to remove the affected bone and replace it with a prosthesis
- Radiation therapy to slow down the progression of the disease
- Physical therapy to help with mobility and reduce pain
- Calcium and vitamin D supplements to maintain bone health
- Regular monitoring of calcium and phosphorus levels in the blood
9 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Paget disease of skull - Prevention
Paget disease of the skull can be prevented by ensuring adequate amounts of calcium and vitamin d in the diet, avoiding excessive alcohol consumption, and avoiding exposure to loud noises. additionally, regular exercise and a healthy lifestyle can help reduce the risk of developing this condition.