(N06.5) Isolated proteinuria with specified morphological lesion : diffuse mesangiocapillary glomerulonephritis

Isolated proteinuria with specified morphological lesion : diffuse mesangiocapillary glomerulonephritis is a type of glomerulonephritis characterized by inflammation of the glomeruli, which are the tiny filters in the kidney that are responsible for filtering out waste products from the blood. this type of glomerulonephritis is caused by an autoimmune response that leads to the formation of immune complexes of antibodies and antigens, which deposit in the glomeruli, causing damage and inflammation. this leads to proteinuria, or the presence of protein in the urine, as well as other symptoms such as edema, hypertension, and hematuria.

Isolated proteinuria with diffuse mesangiocapillary glomerulonephritis is a condition caused by an autoimmune reaction that targets the glomeruli of the kidneys. this reaction leads to injury of the glomerular capillary walls, resulting in an increased permeability to proteins, which are then excreted in the urine. this increased permeability also leads to increased levels of immunoglobulins, complement, and other inflammatory mediators in the glomerular filtrate, which further damages the glomerular capillaries and causes inflammation of the mesangium. this leads to the formation of scar tissue and a decrease in the number of functioning glomeruli, resulting in proteinuria.

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Main goal of the treatment: To reduce the proteinuria and reverse the morphological lesion of diffuse mesangiocapillary glomerulonephritis.

• Prescription of corticosteroids and immunosuppressants.
• Reduction of salt intake.
• Intravenous administration of immunoglobulin.
• Control of hypertension.
• Monitoring of renal function.
• Regular follow-up of proteinuria.
• Regular monitoring of blood pressure.
• Avoidance of nephrotoxic drugs.
• Regular urine analysis.
• Regular blood tests.

The best way to prevent isolated proteinuria with specified morphological lesion: diffuse mesangiocapillary glomerulonephritis is to maintain a healthy lifestyle, including regular exercise, a balanced diet, and avoiding smoking and alcohol. additionally, it is important to monitor any existing medical conditions, such as diabetes and hypertension, and ensure that they are managed appropriately. vaccinations can also help to reduce the risk of contracting the disease.