Glomerular disorders in diabetes mellitus - what does this mean
Glomerular disorders in diabetes mellitus occur when the high blood sugar levels associated with diabetes damage the tiny blood vessels in the kidneys, known as glomeruli, causing them to become inflamed and unable to filter waste or excess fluid properly. this can lead to a build-up of toxins in the body and, if left untreated, can lead to kidney failure.
What happens during the disease - glomerular disorders in diabetes mellitus
Glomerular disorders in diabetes mellitus are caused by a combination of factors, including the effects of chronic hyperglycemia on the glomerular basement membrane, increased glomerular permeability, and the effects of advanced glycation end-products on glomerular cells and the extracellular matrix. these effects lead to an increase in glomerular filtration rate, proteinuria, and albuminuria, which can ultimately lead to renal failure.
Treatment and Medical Assistance
Main goal of the treatment: To reduce the risk of kidney damage and other complications associated with glomerular disorders in diabetes mellitus.
- Regular monitoring of blood glucose levels
- Management of blood pressure
- Control of cholesterol levels
- Reduction of dietary salt intake
- Regular exercise
- Adequate hydration
- Weight loss and maintenance of healthy body weight
- Smoking cessation
- Medication to control high blood sugar levels and reduce inflammation
- Avoidance of non-steroidal anti-inflammatory drugs (NSAIDs)
- Prescription of angiotensin-converting enzyme inhibitors (ACE inhibitors) or angiotensin receptor blockers (ARBs)
No Hospitalization Required
Average Time for Outpatient Care Not Established
Glomerular disorders in diabetes mellitus - Prevention
The best way to prevent glomerular disorders in diabetes mellitus is to maintain good blood sugar control and to keep the a1c level below 7%. additionally, regular exercise, a healthy diet, and regular visits to the doctor for monitoring can help to prevent or delay the onset of glomerular disorders in diabetes mellitus.