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(C94.2) Acute megakaryoblastic leukaemia
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120 090 in individuals diagnosis acute megakaryoblastic leukaemia confirmed
16 667 deaths with diagnosis acute megakaryoblastic leukaemia
14% mortality rate associated with the disease acute megakaryoblastic leukaemia
Diagnosis acute megakaryoblastic leukaemia is diagnosed Men are 17.58% more likely than Women
70 602
Men receive the diagnosis acute megakaryoblastic leukaemia
8 490 (12.0 %)Died from this diagnosis.
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49 488
Women receive the diagnosis acute megakaryoblastic leukaemia
8 177 (16.5 %)Died from this diagnosis.
Risk Group for the Disease acute megakaryoblastic leukaemia - Men aged 60-64 and Women aged 70-74
In Men diagnosis is most often set at age 0-14, 20-95+
Less common in men the disease occurs at Age 15-19Less common in women the disease occurs at Age 5-9, 15-19, 35-39, 95+
In Women diagnosis is most often set at age 0-5, 10-14, 20-34, 40-94
Disease Features acute megakaryoblastic leukaemia
Absence or low individual and public risk
Acute megakaryoblastic leukaemia - what does this mean
Acute megakaryoblastic leukaemia is a type of cancer of the bone marrow in which the bone marrow produces too many immature megakaryocytes, which are cells that normally produce platelets. this leads to an accumulation of immature cells in the marrow, which can interfere with the production of normal red and white blood cells, leading to anaemia, infection, and other symptoms.
What happens during the disease - acute megakaryoblastic leukaemia
Acute megakaryoblastic leukaemia is a type of acute myeloid leukaemia caused by a genetic mutation in the bone marrow, resulting in the uncontrolled production of immature megakaryocytes (platelets) and myeloblasts (white blood cells). this mutation interferes with the normal maturation of megakaryocytes, causing them to remain immature and unable to perform their normal function. as a result, the body is unable to produce sufficient healthy blood cells, leading to anaemia, infections, and other symptoms of leukaemia.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete Blood Count (CBC)
- Bone Marrow Biopsy
- Flow Cytometry
- Cytogenetic Analysis
- Immunophenotyping
- Molecular Testing
- X-Ray
- CT Scan
- MRI Scan
Treatment and Medical Assistance
Main Goal: To reduce the number of cancer cells in the body and to prevent the spread of cancer.
- Chemotherapy
- Radiation therapy
- Targeted therapy
- Stem cell transplant
- Surgery
- Immunotherapy
- Gene therapy
- Hormone therapy
14 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Acute megakaryoblastic leukaemia - Prevention
The best way to prevent acute megakaryoblastic leukaemia is to reduce exposure to environmental and chemical toxins, maintain a healthy lifestyle, and seek regular medical checkups. additionally, avoiding smoking, maintaining a healthy weight, and eating a balanced diet can help reduce the risk of developing the disease.