(P53) Haemorrhagic disease of fetus and newborn

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25 606 in individuals diagnosis haemorrhagic disease of fetus and newborn confirmed
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2 111 deaths with diagnosis haemorrhagic disease of fetus and newborn
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8% mortality rate associated with the disease haemorrhagic disease of fetus and newborn

Diagnosis haemorrhagic disease of fetus and newborn is diagnosed Men are 0.95% more likely than Women

12 925

Men receive the diagnosis haemorrhagic disease of fetus and newborn

2 111 (16.3 %)

Died from this diagnosis.

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12 681

Women receive the diagnosis haemorrhagic disease of fetus and newborn

0 (less than 0.1%)

Died from this diagnosis.

Risk Group for the Disease haemorrhagic disease of fetus and newborn - Men and Women aged 0

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In Men diagnosis is most often set at age 0-1
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Less common in men the disease occurs at Age 0-95+Less common in women the disease occurs at Age 0-95+
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In Women diagnosis is most often set at age 0-1

Disease Features haemorrhagic disease of fetus and newborn

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Absence or low individual and public risk
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Haemorrhagic disease of fetus and newborn - what does this mean

Haemorrhagic disease of the fetus and newborn (hdfn) is a rare disorder caused by the mother's antibodies crossing the placenta and attacking the baby's red blood cells. this leads to the destruction of the baby's red blood cells, resulting in anaemia, jaundice, and other complications.

What happens during the disease - haemorrhagic disease of fetus and newborn

Haemorrhagic disease of the fetus and newborn (hdfn) is a condition caused by a deficiency of vitamin k, which is essential for the production of several clotting factors. this deficiency leads to a lack of clotting factors, resulting in a propensity for bleeding. this can manifest in both the fetus and newborn, leading to complications such as intracranial haemorrhaging, which can be life-threatening.

Clinical Pattern

More details coming soon

How does a doctor diagnose

  • Obtain a detailed medical history of the mother and newborn.
  • Perform a physical examination of the newborn.
  • Order laboratory tests to check for clotting factors.
  • Perform a complete blood count to check for anemia.
  • Perform a urinalysis to check for protein in the urine.
  • Perform a chest X-ray to check for pulmonary edema.
  • Perform an ultrasound to check for placental abruption.
  • Perform a magnetic resonance imaging (MRI) scan to check for cerebral hemorrhage.
  • Perform a computed tomography (CT) scan to check for intracranial hemorrhage.
  • Perform an amniocentesis to check for the presence of viruses.
  • Perform a genetic test to check for inherited clotting disorders.

Treatment and Medical Assistance

Main goal of the treatment: To reduce the risk of maternal and neonatal mortality and morbidity.
  • Perform antenatal screening and diagnosis of HDFN.
  • Provide appropriate counseling to the mother and family.
  • Administer Rh immunoglobulin to the mother.
  • Monitor and manage maternal and fetal complications.
  • Provide supportive care to the newborn.
  • Provide nutritional support to the newborn.
  • Perform regular blood transfusions.
  • Provide follow-up care and monitoring.
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12 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Haemorrhagic disease of fetus and newborn - Prevention

The best way to prevent haemorrhagic disease of the fetus and newborn is for expectant mothers to receive a vaccination for the disease during the second trimester of pregnancy. this will ensure that the baby is protected from the disease at birth, and will also provide some protection for the mother during delivery. additionally, it is important to ensure that all newborns receive the appropriate vaccinations to protect them from this potentially dangerous disease.