(Q60.2) Renal agenesis, unspecified
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Diagnosis renal agenesis, unspecified is diagnosed Men are 15.95% more likely than Women
Men receive the diagnosis renal agenesis, unspecified
4 242 (6.4 %)Died from this diagnosis.
Women receive the diagnosis renal agenesis, unspecified
3 773 (7.9 %)Died from this diagnosis.
Risk Group for the Disease renal agenesis, unspecified - Men and Women aged 0
Disease Features renal agenesis, unspecified
Renal agenesis, unspecified - what does this mean
What happens during the disease - renal agenesis, unspecified
Закладка почек происходит путем взаимодействия между мезонефральным протоком, из которого в дальнейшем формируются будущий мочеточник, почечная лоханка и система собирательных трубочек, и нефрогенным зачатком (метанефрической бластемой/мезензхимой), дающим начало нефрону. Процесс нефрогенеза совершается в ранний период развития зародыша, до 6-7 недели эмбриогенеза.
В этот период под действием внешних факторов или мутации генов, ответственных за данный процесс, зачаток мочеточника либо вовсе не развивается из мезонефрального протока, либо не стимулирует окружающую метанефрическую мезенхиму к образованию клубочков и нефронов. Формируется агенезия (одно- или двусторонняя) или рудиментарная нефункционирующая почка (аплазия).
Без обеих почек плод не вырабатывает мочу, которая в норме выводится в околоплодную жидкость. При аплазии обеих почек объем околоплодных вод существенно уменьшается, что приводит к тяжелому ренальному маловодию, компрессии плода. В этих условиях формируются различные деформации, может наступить внутриутробная гибель. Пациенты с односторонней аренией имеют повышенный риск развития ХПН, вызванного общим уменьшением числа нефронов с последующим очаговым гломерулосклерозом.
Clinical Pattern
How does a doctor diagnose
Treatment and Medical Assistance
Renal agenesis, unspecified - Prevention
Main symptoms of the disease renal agenesis, unspecified
Tissue edema
(Fluid retention, Swelling, Puffiness, Fluid accumulation, Bloating, Hydrops, Dropsy, Congestion, Inflammation)
Tissue edema is an accumulation of fluid in the interstitial space of the body. It can occur in any part of the body, but is most commonly seen in the extremities, face, and abdomen. It is characterized by swelling, tenderness, and a feeling of tightness in the affected area. It may develop graduall...
Abdominal pain
(Stomach pain, Bellyache, Tummy ache, Abdominal ache, Gut pain, Intestinal pain, Stomachache, Abdomen pain, Gastric pain, Abdominal discomfort)
Abdominal pain is a common symptom that can range from mild to severe. It often presents as a dull, aching sensation in the abdomen, but can also manifest as sharp or cramping pain. It can be localized to one area or spread across the abdomen. It can develop suddenly or gradually, and can be accompa...
High pressure
(Hypertension, Hypertensive, High blood pressure, Bp, Elevated pressure, Raised pressure, Cardiac stress, Tension, Strain)
High pressure headache is a type of headache that is characterized by a feeling of pressure or tightness around the head. It usually develops slowly, beginning as a dull ache and gradually intensifying to a throbbing or pounding sensation. It can be accompanied by other symptoms such as sensitivity ...
Pain in the pelvis
(Ache in the pelvis, Pelvic discomfort, Pelvic agony, Pelvic soreness, Pelvic hurt, Pelvic ache, Pelvic pain, Pelvic distress, Pelvic suffering, Pelvic anguish)
Pain in the pelvis is a common symptom that can range from mild to severe. It can be caused by a variety of conditions, including inflammation, infection, trauma, and structural abnormalities. It can manifest as a dull ache, sharp pain, or cramping sensation. It can be localized to the lower abdomen...
Nausea
(Upset stomach, Queasiness, Queasy feeling, Stomach discomfort, Gastric unease, Stomach churning, Stomach upset, Stomachache, Feeling sick, Feeling queasy, Stomach queasiness, Feeling nauseous, Feeling nauseated, Nauseousness)
Nausea is an unpleasant feeling in the upper abdomen that may be accompanied by an urge to vomit. It can range from mild to severe and can be accompanied by symptoms such as sweating, dizziness, and increased salivation. Nausea can be caused by a variety of stimuli, including motion sickness, certai...
Polyuria
(Excessive urination, Increased urination, Frequent urination, Excessive thirst, Excessive drinking, Large volume of urine, Excessive urine output, Polydipsia, Profuse urine output)
Polyuria is a symptom of excessive urine output, usually greater than 2.5 liters per day. It is characterized by the need to urinate frequently and produce a large amount of urine each time. Polyuria can be caused by a variety of conditions, including diabetes, kidney disease, and certain medication...
Frequent urination
Frequent urination is a symptom of an underlying medical condition. It is characterized by an increased urge to urinate and the need to urinate more often than usual. It can range from mild to severe in intensity and can be accompanied by other symptoms such as pain, burning, or difficulty starting ...