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Men receive the diagnosis malignant neoplasm: testis, unspecified
29 902 (3.0 %)Died from this diagnosis.
Women receive the diagnosis malignant neoplasm: testis, unspecified
0 (No mortality)Died from this diagnosis.
Окончательная причина возникновения рака яичка до сих пор не установлена, но прослеживается ряд факторов, наличие которых существенно повышает риск развития заболевания.
Выделяют три группы факторов риска: перинатальные (связанные с внутриутробным развитием плода), постпубертатные (относящиеся к периоду развития человека после завершения полового созревания) и генетические.
Перинатальные факторы: установлено, что эстрогены и эстрогеноподобные вещества могут оказывать влияние на внутриутробное формирование гонад у плода. Женские половые гормоны способны индуцировать возникновение тетраплоидии герминогенных клеток (редкий вариант хромосомных аномалий, при котором увеличивается полный набор хромосом зародышевых клеток). Это является одним из признаков развития у плода carcinoma in situ (предшественницы всех раков).
Генетические факторы риска: описана связь между генетическими изменениями (в гене-супрессоре опухоли PTEN) и риском возникновения опухолей половых клеток яичка.
Крипторхизм (неопущение яичка) увеличивает риск развития рака яичка в 5-10 раз. В утробе матери у плода мужского пола развитие яичек происходит в брюшной полости.
Обычно яички опускаются в полость мошонки при рождении или на первом году жизни. Если этот процесс задерживается или яички не опустились в мошонку, создаются неблагоприятные условия, способствующие развитию дегенеративных изменений. Чем глубже и дольше яичко расположено в брюшной полости, тем сильнее нарушается сперматогенная (репродуктивная) функция мужчины.
(Impotence, Ed, Male impotence, Erection problem, Erectile dysfunction, Weak erection, Sexual dysfunction, Male sexual dysfunction, Male sexual impotence, Male erection problem)
Erectile dysfunction is a condition in which a man is unable to achieve or maintain an erection suitable for sexual intercourse. Symptoms can range from a complete inability to achieve an erection or maintain it for a sufficient time, to a partial inability to do so. The condition can develop gradua...
(Fluid retention, Swelling, Puffiness, Fluid accumulation, Bloating, Hydrops, Dropsy, Congestion, Inflammation)
Tissue edema is an accumulation of fluid in the interstitial space of the body. It can occur in any part of the body, but is most commonly seen in the extremities, face, and abdomen. It is characterized by swelling, tenderness, and a feeling of tightness in the affected area. It may develop graduall...
(Swollen lymph nodes, Enlarged lymph glands, Inflamed lymph nodes, Bulging lymph nodes, Tender lymph nodes, Enlarged lymph nodes, Swollen lymph glands, Inflamed lymph glands, Bulging lymph glands, Tender lymph glands)
Enlarged lymph nodes are swellings in the lymphatic system that can range in size from pea-sized to the size of a golf ball. They can develop in the neck, armpit, or groin and are usually painless. They can be caused by infection, inflammation, or cancer and may be accompanied by fever, night sweats...
(Lump in testicle, Hardness in testicle, Bulge in testicle, Swelling in testicle, Knot in testicle, Pain in testicle, Nodule in testicle)
Seal in the testicle is a symptom of an underlying medical condition. It is characterized by a feeling of heaviness, pressure, or pain in the testicles, which can range from mild to severe. It may also be accompanied by a lump or swelling in the testicles. This symptom can develop gradually over tim...
(Scrotal pain, Testicular pain, Groin pain, Scrotal ache, Testicle ache, Groin ache, Scrotal discomfort, Testicle discomfort, Groin discomfort)
Pain in the testicles is a common symptom that can be caused by a variety of medical conditions. It can be a sharp, dull, or burning sensation that can be localized or diffuse. It can range from mild to severe and can come on suddenly or gradually. It can be accompanied by other symptoms such as swe...
(Male breast enlargement, Man boobs, Male breast development, Glandular mammary hypertrophy, Pseudogynecomastia, Adipomastia, Mammary hypertrophy, Feminizing mammary gland hyperplasia)
Gynecomastia is a condition in which the breasts become enlarged in males due to a hormonal imbalance. It is characterized by swelling of the breast tissue and can occur in one or both breasts. It is most common in teenage boys, but can occur in adults as well. It usually develops gradually over tim...
(Back pain, Dorsalgia, Lumbago, Sciatica, Thoracic pain, Lumbar strain, Spinal pain, Sacroiliac pain, Muscle spasm, Osteoarthritis pain)
Backache is a common symptom of musculoskeletal pain, usually felt as an ache or stiffness in the lower back. It can develop gradually or suddenly, and can range from mild to severe. Common causes of backache include poor posture, muscular strain, injury, or overuse. Symptoms can include pain in the...
(Absence of urine, Decreased urine output, Low urine output, Reduced urine production, Suppressed urine production)
Anuria and oliguria are medical terms used to describe a decreased output of urine. Anuria is a complete absence of urine and oliguria is a decreased output of urine. These symptoms can be caused by a number of conditions, such as kidney failure, dehydration, or blockage in the urinary tract. Sympto...
(Hack, Wheeze, Hacking, Coughing, Rales, Choking, Gasping, Barking, Hemoptysis, Whooping, Pertussis)
Coughing is a reflex action that helps clear airways of irritants and mucus. It usually begins as a dry, tickling sensation in the back of the throat that causes an uncontrollable urge to cough. It can range from a mild, intermittent annoyance to a severe, hacking cough that produces thick mucus. It...
(Shortness of breath, Labored breathing, Breathlessness, Air hunger, Difficulty breathing, Gasping, Panting, Wheezing, Tightness in chest, Suffocating feeling)
Dyspnea is a feeling of breathlessness or difficulty breathing. It can range from mild to severe and can be caused by a variety of factors, such as asthma, COPD, heart failure, or anemia. Symptoms of dyspnea may include shortness of breath, wheezing, chest tightness, and rapid breathing. Dyspnea can...