Poisoning: anticholinesterase agents - what does this mean
Poisoning by anticholinesterase agents occurs when these compounds, which inhibit the enzyme acetylcholinesterase, interfere with the breakdown of acetylcholine, a neurotransmitter. this results in an overstimulation of cholinergic receptors, leading to a range of symptoms, including excessive salivation, sweating, nausea, vomiting, abdominal cramps, diarrhea, and muscle weakness.
What happens during the disease - poisoning: anticholinesterase agents
Poisoning by anticholinesterase agents results from the inhibition of acetylcholinesterase, an enzyme that is responsible for the breakdown of acetylcholine in the synaptic cleft. this inhibition leads to an accumulation of acetylcholine, which causes an overstimulation of the parasympathetic nervous system and muscarinic and nicotinic receptors. the resulting symptoms include nausea, vomiting, abdominal cramps, diarrhea, increased salivation, bronchoconstriction, bradycardia, hypotension, and muscle weakness.
Treatment and Medical Assistance
Main Goal: Treat Poisoning with Anticholinesterase Agents
- Administer an antidote to counteract the effects of the poison
- Provide supportive care such as oxygen, IV fluids, and monitoring of vital signs
- Administer anticholinesterase agents to reduce the effects of the poison
- Monitor patient for signs of respiratory depression and other complications
- Provide nutrition and hydration as needed
- Monitor for signs of infection
- Administer medications to reduce pain, nausea, and other symptoms
- Provide psychological support and counseling
6 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Poisoning: anticholinesterase agents - Prevention
The best way to prevent poisoning from anticholinesterase agents is to avoid contact with these substances, use proper protective equipment, and store them in a secure location. additionally, it is important to be aware of the signs and symptoms of poisoning and seek medical attention immediately if any are present.