(T44.0) Poisoning: anticholinesterase agents

More details coming soon

Icon
140 805 in individuals diagnosis poisoning: anticholinesterase agents confirmed

Diagnosis poisoning: anticholinesterase agents is diagnosed Women are 11.20% more likely than Men

62 514

Men receive the diagnosis poisoning: anticholinesterase agents

0 (less than 0.1%)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
78 291

Women receive the diagnosis poisoning: anticholinesterase agents

0 (less than 0.1%)

Died from this diagnosis.

Risk Group for the Disease poisoning: anticholinesterase agents - Men and Women aged 0-5

Icon
In Men diagnosis is most often set at age 0-89
Icon
Less common in men the disease occurs at Age 90-95+Less common in women the disease occurs at Age 95+
Icon
In Women diagnosis is most often set at age 0-94

Disease Features poisoning: anticholinesterase agents

Icon
Absence or low individual and public risk
Icon

Poisoning: anticholinesterase agents - what does this mean

Poisoning by anticholinesterase agents occurs when these compounds, which inhibit the enzyme acetylcholinesterase, interfere with the breakdown of acetylcholine, a neurotransmitter. this results in an overstimulation of cholinergic receptors, leading to a range of symptoms, including excessive salivation, sweating, nausea, vomiting, abdominal cramps, diarrhea, and muscle weakness.

What happens during the disease - poisoning: anticholinesterase agents

Poisoning by anticholinesterase agents results from the inhibition of acetylcholinesterase, an enzyme that is responsible for the breakdown of acetylcholine in the synaptic cleft. this inhibition leads to an accumulation of acetylcholine, which causes an overstimulation of the parasympathetic nervous system and muscarinic and nicotinic receptors. the resulting symptoms include nausea, vomiting, abdominal cramps, diarrhea, increased salivation, bronchoconstriction, bradycardia, hypotension, and muscle weakness.

Clinical Pattern

More details coming soon

How does a doctor diagnose

  • Blood tests to measure levels of anticholinesterase agents
  • Urine tests to detect anticholinesterase agents
  • Imaging tests such as CT scans or MRI scans to identify any organ damage
  • Liver function tests to check for any damage to the liver
  • Neurological tests to evaluate any nerve damage
  • Tests to measure levels of enzymes in the blood
  • Tests to measure levels of enzymes in the urine
  • Tests to measure levels of toxins in the blood
  • Tests to measure levels of toxins in the urine
  • Skin tests to detect any allergic reactions
  • Breathing tests to check for any respiratory problems

Treatment and Medical Assistance

Main Goal: Treat Poisoning with Anticholinesterase Agents
  • Administer an antidote to counteract the effects of the poison
  • Provide supportive care such as oxygen, IV fluids, and monitoring of vital signs
  • Administer anticholinesterase agents to reduce the effects of the poison
  • Monitor patient for signs of respiratory depression and other complications
  • Provide nutrition and hydration as needed
  • Monitor for signs of infection
  • Administer medications to reduce pain, nausea, and other symptoms
  • Provide psychological support and counseling
Icon
6 Days of Hospitalization Required
Icon
Average Time for Outpatient Care Not Established

Poisoning: anticholinesterase agents - Prevention

The best way to prevent poisoning from anticholinesterase agents is to avoid contact with these substances, use proper protective equipment, and store them in a secure location. additionally, it is important to be aware of the signs and symptoms of poisoning and seek medical attention immediately if any are present.