(T60.0) Toxic effect: organophosphate and carbamate insecticides

More details coming soon

Icon
97 927 in individuals diagnosis toxic effect: organophosphate and carbamate insecticides confirmed

Diagnosis toxic effect: organophosphate and carbamate insecticides is diagnosed Men are 27.34% more likely than Women

62 352

Men receive the diagnosis toxic effect: organophosphate and carbamate insecticides

0 (less than 0.1%)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
35 575

Women receive the diagnosis toxic effect: organophosphate and carbamate insecticides

0 (less than 0.1%)

Died from this diagnosis.

Risk Group for the Disease toxic effect: organophosphate and carbamate insecticides - Men and Women aged 0-5

Icon
In Men diagnosis is most often set at age 0-89
Icon
Less common in men the disease occurs at Age 90-95+Less common in women the disease occurs at Age 95+
Icon
In Women diagnosis is most often set at age 0-94

Disease Features toxic effect: organophosphate and carbamate insecticides

Icon
Absence or low individual and public risk
Icon

Toxic effect: organophosphate and carbamate insecticides - what does this mean

Organophosphate and carbamate insecticides are toxic chemicals that disrupt the normal functioning of the nervous system by inhibiting the enzyme acetylcholinesterase, leading to an accumulation of the neurotransmitter acetylcholine. this can cause a wide range of symptoms, including muscle weakness, confusion, nausea, vomiting, and respiratory distress. in severe cases, it can lead to paralysis, coma, and death.

What happens during the disease - toxic effect: organophosphate and carbamate insecticides

Toxic effects of organophosphate and carbamate insecticides occur when these compounds bind to and inhibit the activity of acetylcholinesterase, an enzyme responsible for breaking down the neurotransmitter acetylcholine. this leads to an accumulation of acetylcholine in the synapses, resulting in an overstimulation of the muscarinic and nicotinic receptors, leading to the various symptoms associated with this toxicity.

Clinical Pattern

More details coming soon

How does a doctor diagnose

  • Blood test to measure levels of acetylcholinesterase (AChE) activity
  • Urine test to measure levels of organophosphate metabolites
  • Liver function tests
  • Imaging scans to check for any organ damage
  • Neurological tests to check for any nerve damage
  • Skin prick tests to check for allergic reactions
  • Pulmonary function tests to check for any respiratory damage

Treatment and Medical Assistance

Main Goal: Treating the toxic effect of organophosphate and carbamate insecticides
  • Provide supportive care, including oxygen and airway management
  • Administer atropine to counteract the muscarinic effects of organophosphates and carbamates
  • Administer pralidoxime to counteract the nicotinic effects of organophosphates
  • Administer benzodiazepines to counteract the central nervous system depression caused by organophosphates and carbamates
  • Administer fluids and electrolytes to prevent dehydration and electrolyte imbalances
  • Monitor vital signs, such as heart rate, respiratory rate, and blood pressure
  • Monitor for signs of respiratory distress and other complications
  • Monitor for signs of recurrent poisoning, such as excessive sweating, nausea, vomiting, and diarrhea
  • Provide psychological support to the patient
Icon
5 Days of Hospitalization Required
Icon
Average Time for Outpatient Care Not Established

Toxic effect: organophosphate and carbamate insecticides - Prevention

The best way to prevent toxic effects from organophosphate and carbamate insecticides is to use them only when absolutely necessary and to follow the instructions on the label carefully. it is also important to wear protective clothing and a mask when using these insecticides and to avoid breathing in any of the spray. finally, it is essential to store these products in a secure place, away from children and pets.