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(J70.2) Acute drug-induced interstitial lung disorders
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99 238 in individuals diagnosis acute drug-induced interstitial lung disorders confirmed
5 233 deaths with diagnosis acute drug-induced interstitial lung disorders
5% mortality rate associated with the disease acute drug-induced interstitial lung disorders
Diagnosis acute drug-induced interstitial lung disorders is diagnosed Men are 3.52% more likely than Women
51 367
Men receive the diagnosis acute drug-induced interstitial lung disorders
2 686 (5.2 %)Died from this diagnosis.
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47 871
Women receive the diagnosis acute drug-induced interstitial lung disorders
2 547 (5.3 %)Died from this diagnosis.
Risk Group for the Disease acute drug-induced interstitial lung disorders - Men aged 70-74 and Women aged 80-84
In Men diagnosis is most often set at age 0-94
Less common in men the disease occurs at Age 95+Less common in women the disease occurs at Age 25-29
In Women diagnosis is most often set at age 0-24, 30-95+
Disease Features acute drug-induced interstitial lung disorders
Absence or low individual and public risk
Acute drug-induced interstitial lung disorders - what does this mean
Acute drug-induced interstitial lung disorders occur when the lung tissue becomes inflamed due to an allergic reaction to a drug. the inflammation causes the air sacs in the lungs to become scarred and narrowed, leading to difficulty breathing, coughing, and wheezing.
What happens during the disease - acute drug-induced interstitial lung disorders
Acute drug-induced interstitial lung disorders are caused by a direct toxic effect of certain drugs on the alveolar walls and pulmonary interstitium, leading to inflammation, fibrosis, and ultimately impaired gas exchange. this can be caused by a single large dose or prolonged use of certain medications, such as amiodarone, nitrofurantoin, and bleomycin.
Clinical Pattern
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How does a doctor diagnose
- Obtain a detailed medical history, including current and past medications.
- Perform a physical examination, focusing on the lungs.
- Order a chest X-ray.
- Order a high-resolution computed tomography (HRCT) scan.
- Order pulmonary function tests.
- Order a bronchoalveolar lavage.
- Order a transbronchial biopsy.
- Order an open lung biopsy.
- Order blood tests to measure levels of certain drugs.
Treatment and Medical Assistance
Main goal of the treatment: Reduce inflammation and improve lung function
- Prescribe corticosteroids to reduce inflammation
- Administer oxygen therapy to improve oxygen levels in the blood
- Prescribe bronchodilators to open airways and improve breathing
- Educate patient on proper inhaler technique
- Perform pulmonary function tests to evaluate lung function
- Prescribe antibiotics to treat any underlying infections
- Administer immunosuppressants to reduce inflammation
- Prescribe anti-inflammatory drugs to reduce inflammation
- Perform imaging tests to evaluate the lungs
- Recommend lifestyle changes to improve lung health
20 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Acute drug-induced interstitial lung disorders - Prevention
Acute drug-induced interstitial lung disorders can be prevented by avoiding or minimizing the use of drugs that are known to cause this condition, such as certain antibiotics, antifungals, and chemotherapy agents. additionally, it is important to be aware of the potential side effects of any medications that are being taken and to seek medical attention if any respiratory symptoms develop.