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(D80.3) Selective deficiency of immunoglobulin g [igg] subclasses
More details coming soon
230 829 in individuals diagnosis selective deficiency of immunoglobulin g [igg] subclasses confirmed
3 237 deaths with diagnosis selective deficiency of immunoglobulin g [igg] subclasses
1% mortality rate associated with the disease selective deficiency of immunoglobulin g [igg] subclasses
Diagnosis selective deficiency of immunoglobulin g [igg] subclasses is diagnosed Men are 29.67% more likely than Women
149 656
Men receive the diagnosis selective deficiency of immunoglobulin g [igg] subclasses
1 396 (0.9 %)Died from this diagnosis.
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81 173
Women receive the diagnosis selective deficiency of immunoglobulin g [igg] subclasses
1 841 (2.3 %)Died from this diagnosis.
Risk Group for the Disease selective deficiency of immunoglobulin g [igg] subclasses - Men and Women aged 0-5
In Men diagnosis is most often set at age 0-89
Less common in men the disease occurs at Age 90-95+Less common in women the disease occurs at Age 35-39, 85-95+
In Women diagnosis is most often set at age 0-34, 40-84
Disease Features selective deficiency of immunoglobulin g [igg] subclasses
Absence or low individual and public risk
Selective deficiency of immunoglobulin g [igg] subclasses - what does this mean
Selective deficiency of immunoglobulin g (igg) subclasses is caused by a decrease in the production of specific antibodies due to a lack of certain immune system components. this can be caused by genetic disorders, infections, or certain medical conditions. the result is an impaired ability to fight off infections, leading to increased susceptibility to certain illnesses.
What happens during the disease - selective deficiency of immunoglobulin g [igg] subclasses
Selective deficiency of immunoglobulin g subclasses is caused by genetic defects in the b-cell maturation process, leading to impaired production of igg subclasses. this defect in b-cell maturation can be caused by gene mutations, a deficiency of certain hormones, or an underlying autoimmune disorder. as a result, the patient will have reduced levels of igg subclasses and an increased risk of recurrent and severe bacterial infections.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete blood count
- Serum protein electrophoresis
- Quantitative immunoglobulin assay
- IgG subclasses assay
- Flow cytometry
- T-cell functional assays
- Cell-mediated immunity testing
Treatment and Medical Assistance
Main goal of the treatment: To replenish IgG subclasses in the body.
- Administering intravenous immunoglobulin (IVIG) therapy
- Replacing lost immunoglobulins with IgG concentrate
- Providing nutritional support
- Prescribing antibiotics to prevent infections
- Performing regular blood tests to monitor IgG levels
- Providing vaccinations to prevent infection
- Providing education and lifestyle advice on how to reduce the risk of infection
7 Days of Hospitalization Required
126 Hours Required for Outpatient Treatment
Selective deficiency of immunoglobulin g [igg] subclasses - Prevention
Prevention of selective deficiency of immunoglobulin g [igg] subclasses involves immunizing against common childhood diseases, such as measles, mumps, and rubella, as well as avoiding exposure to certain infections, such as epstein-barr virus. additionally, it is important to ensure adequate nutrition, as a healthy diet can help to support the immune system. supplementation with probiotics may also be beneficial in some cases.