(D56) Thalassaemia

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20 434 in individuals diagnosis thalassaemia confirmed
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3 007 deaths with diagnosis thalassaemia
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15% mortality rate associated with the disease thalassaemia

Diagnosis thalassaemia is diagnosed Women are 1.40% more likely than Men

10 074

Men receive the diagnosis thalassaemia

1 039 (10.3 %)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
10 360

Women receive the diagnosis thalassaemia

1 968 (19.0 %)

Died from this diagnosis.

Risk Group for the Disease thalassaemia - Men aged 30-34 and Women aged 5-9

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In Men diagnosis is most often set at age 0-19, 25-54, 60-64, 75-89
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Less common in men the disease occurs at Age 20-24, 55-59, 65-74, 90-95+Less common in women the disease occurs at Age 40-44, 70-74, 90-95+
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In Women diagnosis is most often set at age 0-39, 45-69, 75-89

Disease Features thalassaemia

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Non-contagious
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Moderate individual risk, low public risk
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Thalassaemia - what does this mean

Thalassaemia is a genetic blood disorder caused by mutations in the genes responsible for the production of haemoglobin, the protein in red blood cells that carries oxygen throughout the body. this results in a reduced production of haemoglobin and red blood cells, leading to anaemia, fatigue, and other complications.

What happens during the disease - thalassaemia

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Clinical Pattern

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How does a doctor diagnose

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Treatment and Medical Assistance

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7 Days of Hospitalization Required
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83 Hours Required for Outpatient Treatment

Thalassaemia - Prevention

Thalassaemia can be prevented by pre-conception screening, pre-natal diagnosis and antenatal counselling. couples who are at risk of having a child with thalassaemia should consider genetic counselling and testing to determine their risk. vaccinations and iron chelation therapy can also help to reduce the risk of thalassaemia.

Main symptoms of the disease thalassaemia

Dizziness

(Vertigo, Lightheadedness, Giddiness, Faintness, Unsteadiness, Dazed, Spinning, Disorientation, Unbalanced, Foggy, Loss of balance, Uncoordinated, Confusion)

Dizziness is a sensation of feeling off-balance and lightheaded. It can range from mild to severe and can be accompanied by a feeling of spinning or swaying. It can develop suddenly or gradually, and can be triggered by physical activity, changes in position, or lack of food or fluids. Symptoms can ...

Age: 1 to 100Accociated with 133 diseases

Heart rhythm disorder

(Arrhythmia, Cardiac arrhythmia, Irregular heartbeat, Cardiac dysrhythmia, Cardiac rhythm disorder, Heart rhythm disturbance, Heart rhythm irregularity, Cardiac rhythm irregularity, Abnormal heartbeat, Heartbeat disorder)

Heart rhythm disorder is a condition where the heart beats irregularly or too quickly or too slowly. It can manifest as palpitations, lightheadedness, chest pain, fatigue, or shortness of breath. It can develop from a variety of causes, including lifestyle factors, medications, and underlying medica...

Age: any ageAccociated with 48 diseases

Dementia

Dementia is a symptom of a wide range of conditions that affect the brain. It is characterised by a decline in cognitive function, including memory, language, problem-solving, and judgement. It can also affect behaviour, emotions, and the ability to perform everyday activities. Symptoms typically de...

Age: 1 to 100Accociated with 19 diseases

Malocclusion

(Bad bite, Crooked teeth, Misaligned teeth, Misalignment of teeth, Overbite, Underbite, Teeth crowding, Teeth overlapping, Teeth misalignment, Malpositioned teeth, Teeth displacement, Malocclusion of teeth)

Malocclusion is an abnormal bite caused by misalignment of the upper and lower teeth. It can range from mild to severe, with symptoms including crowded teeth, protruding teeth, and misaligned jaw. It can develop due to genetics, injury, or an incorrect swallowing pattern. This condition can cause pa...

Age: any ageAccociated with 3 diseases

Pale skin

Pale skin is a symptom of anemia or other blood-related issues. It is characterized by a lack of color in the skin, appearing wan and ashen. It may also be accompanied by fatigue, dizziness, and shortness of breath. Pale skin develops gradually due to a decrease in red blood cells or hemoglobin, whi...

Age: 1 to 100Accociated with 96 diseases

Jaundice

(Icterus, Yellowing, Xanthochromia, Yellowing of the skin, Icteric, Icteroid, Yellow discoloration, Yellowing of the eyes, Xanthous, Icterus gravis, Icteric sclera)

Jaundice is a yellow discoloration of the skin, eyes, and mucous membranes caused by a buildup of bilirubin in the body. It usually develops gradually and is characterized by a yellowish tint to the skin, whites of the eyes, and mucous membranes. It can range from mild to severe, depending on the un...

Age: any ageAccociated with 60 diseases

Headache

(Cephalalgia, Hedache, Pounding head, Throbbing head, Ache, Pounding pain, Throbbing pain, Head pain, Migraine, Tension headache)

Headache is a common symptom that can range from mild to severe. It typically develops gradually and can be localized or generalized. Common types of headache include tension-type, migraine, cluster, and sinus headaches, each with their own unique characteristics and manifestations. Tension-type hea...

Age: 1 to 100Accociated with 244 diseases

Delayed stages of development

(Retardation, Sluggishness, Arrested growth, Backwardness, Lateness, Stunted growth, Slow progress, Lag, Slowness, Stagnation)

Delayed stages of development is a symptom where a person is not meeting the expected milestones for their age. It can manifest as a lack of certain skills, such as speech, physical coordination, or cognitive abilities. It can also appear as a slower rate of development than peers, such as taking lo...

Age: 1 to 100Accociated with 19 diseases
Liver enlargement

Liver enlargement

(Hepatomegaly, Hepatic enlargement, Liver swelling, Hepatitis, Hepatomegalic, Hepatomegalia, Hepatosplenomegaly, Hepatomegalies, Hepatomegaly syndrome, Hepatic enlargement disorder)

Liver enlargement is a symptom of an underlying medical condition. It is characterized by an increase in the size of the liver, which can be felt in the right upper abdomen. It may develop gradually or suddenly, and can be accompanied by pain, nausea, vomiting, and jaundice. It can manifest as an en...

Age: 1 to 100Accociated with 49 diseases
Enlargement of the tear

Enlargement of the tear

(Expansion of the tear, Tear swelling, Augmentation of the tear, Tear enlargement, Tear dilatation, Tear distention, Tear extension)

Enlargement of the tear duct is a symptom which is characterized by an increase in the size of the tear duct. It may be accompanied by a feeling of fullness or pressure in the eyes, and can cause excessive tearing. It usually develops gradually over time, and its manifestations can vary depending on...

Age: 1 to 100Accociated with 32 diseases
Ulcer external

Ulcer external

(Open sore, Lesion, Sore, Cut, Wound, Gash, Abrasion, Laceration, Scratch, Bruise)

Ulcer external is a type of skin lesion that is caused by a break in the skin, leading to an open sore. It usually appears as a red, raised area that is often painful and may have a yellowish or white pus-filled center. The area around the ulcer may be swollen and warm to the touch. Ulcer external c...

Age: 1 to 100Accociated with 39 diseases

Weakness

Weakness is a lack of strength and energy that can range from mild to severe. It can be a symptom of a wide range of conditions, including physical and mental exhaustion, chronic illnesses, and certain medications. It can also be caused by a lack of nutrients, dehydration, or an underlying medical c...

Age: any ageAccociated with 291 diseases

Specified forms of the disease

(D56.0) Alpha thalassaemia
(D56.1) Beta thalassaemia
(D56.2) Delta-beta thalassaemia
(D56.3) Thalassaemia trait
(D56.4) Hereditary persistence of fetal haemoglobin [HPFH]
(D56.8) Other thalassaemias
(D56.9) Thalassaemia, unspecified