(D70) Agranulocytosis

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724 793 in individuals diagnosis agranulocytosis confirmed
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12 893 deaths with diagnosis agranulocytosis
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2% mortality rate associated with the disease agranulocytosis

Diagnosis agranulocytosis is diagnosed Women are 6.90% more likely than Men

337 402

Men receive the diagnosis agranulocytosis

7 608 (2.3 %)

Died from this diagnosis.

100
95
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75
70
65
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55
50
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5
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387 391

Women receive the diagnosis agranulocytosis

5 285 (1.4 %)

Died from this diagnosis.

Risk Group for the Disease agranulocytosis - Men and Women aged 65-69

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In Men diagnosis is most often set at age 0-94
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Less common in men the disease occurs at Age 95+Less common in women the disease occurs at Age 95+
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In Women diagnosis is most often set at age 0-94

Disease Features agranulocytosis

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Absence or low individual and public risk
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Agranulocytosis - what does this mean

Agranulocytosis is a rare but serious condition in which the body produces an abnormally low number of white blood cells, which are responsible for fighting infection. it is caused by a variety of factors, including certain medications, infections, autoimmune diseases, and exposure to radiation or toxic chemicals.

What happens during the disease - agranulocytosis

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Clinical Pattern

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How does a doctor diagnose

  • Complete Blood Count (CBC)
  • Differential Blood Count (DBC)
  • Bone Marrow Biopsy
  • Immunophenotyping
  • Flow Cytometry
  • Cytogenetic Analysis
  • Serum Protein Electrophoresis
  • Serum Immunoglobulin Levels
  • Skin Test for Tuberculosis
  • Skin Prick Test

Treatment and Medical Assistance

Main Goal: Treat Agranulocytosis
  • Monitor white blood cell count and other blood tests regularly
  • Provide antibiotics to treat any infections
  • Provide medications to stimulate the bone marrow to produce more white blood cells
  • Provide supportive treatments, such as oxygen therapy and intravenous fluids, if needed
  • Provide transfusions of white blood cells, if needed
  • Provide supportive treatments, such as nutritional supplements, to help the body heal
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14 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Agranulocytosis - Prevention

Agranulocytosis can be prevented by avoiding certain medications that are known to cause the condition, such as antithyroid drugs, antipsychotics, and some antibiotics. additionally, regular monitoring of white blood cell count is recommended for those taking these medications. other preventive measures include avoiding exposure to toxins, radiation, and extreme temperatures.

Main symptoms of the disease agranulocytosis

Weakness

Weakness is a lack of strength and energy that can range from mild to severe. It can be a symptom of a wide range of conditions, including physical and mental exhaustion, chronic illnesses, and certain medications. It can also be caused by a lack of nutrients, dehydration, or an underlying medical c...

Age: any ageAccociated with 291 diseases

Fatigue

(Tiredness, Exhaustion, Lethargy, Lassitude, Weariness, Burn-out, Weakness, Malaise, Lack of energy, Lack of strength, Listlessness)

Fatigue is a common symptom that can range from mild to severe. It is usually characterized by a feeling of tiredness and exhaustion that can range from mild to severe. It can develop gradually over time or suddenly, and can be caused by a variety of factors, including physical or mental stress, sle...

Age: 1 to 100Accociated with 157 diseases

Headache

(Cephalalgia, Hedache, Pounding head, Throbbing head, Ache, Pounding pain, Throbbing pain, Head pain, Migraine, Tension headache)

Headache is a common symptom that can range from mild to severe. It typically develops gradually and can be localized or generalized. Common types of headache include tension-type, migraine, cluster, and sinus headaches, each with their own unique characteristics and manifestations. Tension-type hea...

Age: 1 to 100Accociated with 244 diseases

Fever with chills

(Fever with shivering, Fever with trembling, Fever with shaking, Fever with rigors, Fever with quivering, Fever with shuddering, Fever with quaking, Fever with shudder, Fever with trembling rigors, Fever with shuddering fits)

Fever with chills is a common symptom of infection, and is characterized by a sudden onset of high body temperature and shivering. It may be accompanied by other symptoms such as sweating, headache, fatigue, body aches, and general weakness. As the body temperature rises, the patient may experience ...

Age: 1 to 100Accociated with 105 diseases

Joint pain

(Arthritis, Rheumatism, Aches, Stiffness, Inflammation, Tenderness, Soreness, Swollen joints, Stabbing pain, Throbbing pain, Sharp pain, Dull ache)

Joint pain is a common symptom that can range from mild to severe. It is often caused by inflammation or injury to the joints, muscles, or tendons. It can be localized to one joint or affect multiple joints. It can be acute, lasting only a few days or chronic, lasting weeks or months. It may manifes...

Age: any ageAccociated with 130 diseases

A sore throat

(Scratchy throat, Irritated throat, Raw throat, Hoarse throat, Sore throat, Aching throat, Swollen throat, Tender throat, Scratchy feeling in throat, Burning throat)

A sore throat is an inflammation of the throat caused by a virus or bacteria. It usually starts as a scratchy feeling in the throat that progresses to a burning sensation. It is often accompanied by swollen lymph nodes, fever, a runny nose, and a cough. Symptoms can range from mild discomfort to sev...

Age: 1 to 100Accociated with 47 diseases

Plaque on the tonsils

(Coating on the tonsils, Film on the tonsils, Deposit on the tonsils, Accumulation on the tonsils, Buildup on the tonsils, Layer on the tonsils, Residue on the tonsils)

Plaque on the tonsils is a white or yellowish coating that appears on the back of the throat and tonsils. It is usually accompanied by a sore throat and swollen lymph nodes. It can develop slowly over time, or it may appear suddenly. It is caused by a buildup of bacteria and debris, which can be the...

Age: any ageAccociated with 7 diseases
Ulcer external

Ulcer external

(Open sore, Lesion, Sore, Cut, Wound, Gash, Abrasion, Laceration, Scratch, Bruise)

Ulcer external is a type of skin lesion that is caused by a break in the skin, leading to an open sore. It usually appears as a red, raised area that is often painful and may have a yellowish or white pus-filled center. The area around the ulcer may be swollen and warm to the touch. Ulcer external c...

Age: 1 to 100Accociated with 39 diseases

Enlarged lymph nodes

(Swollen lymph nodes, Enlarged lymph glands, Inflamed lymph nodes, Bulging lymph nodes, Tender lymph nodes, Enlarged lymph nodes, Swollen lymph glands, Inflamed lymph glands, Bulging lymph glands, Tender lymph glands)

Enlarged lymph nodes are swellings in the lymphatic system that can range in size from pea-sized to the size of a golf ball. They can develop in the neck, armpit, or groin and are usually painless. They can be caused by infection, inflammation, or cancer and may be accompanied by fever, night sweats...

Age: 1 to 100Accociated with 88 diseases

Smell from the mouth

Bad breath, or halitosis, is a symptom characterized by an unpleasant odor emanating from the mouth. It is usually caused by bacteria on the tongue, teeth, or gums. It can also be caused by poor oral hygiene, dry mouth, certain foods, smoking, or certain medical conditions. Symptoms can range from m...

Age: 1 to 100Accociated with 22 diseases