(D73.0) Hyposplenism

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157 974 in individuals diagnosis hyposplenism confirmed
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4 606 deaths with diagnosis hyposplenism
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3% mortality rate associated with the disease hyposplenism

Diagnosis hyposplenism is diagnosed Men are 8.17% more likely than Women

85 437

Men receive the diagnosis hyposplenism

2 166 (2.5 %)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
72 537

Women receive the diagnosis hyposplenism

2 440 (3.4 %)

Died from this diagnosis.

Risk Group for the Disease hyposplenism - Men aged 60-64 and Women aged 70-74

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In Men diagnosis is most often set at age 0-89
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Less common in men the disease occurs at Age 90-95+Less common in women the disease occurs at Age 95+
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In Women diagnosis is most often set at age 0-94

Disease Features hyposplenism

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Non-contagious
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Moderate individual risk, low public risk
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Hyposplenism - what does this mean

Hyposplenism is a condition in which the spleen does not function properly, resulting in a decrease in the number of red blood cells, white blood cells, and platelets. this is typically caused by conditions such as sickle cell anemia, lupus, and certain types of cancer, as well as certain infections and medications.

What happens during the disease - hyposplenism

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Clinical Pattern

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How does a doctor diagnose

  • Complete Blood Count (CBC)
  • Liver Function Tests (LFTs)
  • Spleen Ultrasound
  • Bone Marrow Biopsy
  • Immunoglobulin Levels
  • Flow Cytometry
  • T-Cell Subsets
  • Serum Immunoelectrophoresis

Treatment and Medical Assistance

Main goal of the treatment: To stimulate the spleen to increase the production of red blood cells.
  • Administering medications such as folic acid or iron supplements
  • Performing regular vaccinations to prevent infection
  • Prescribing antibiotics to reduce the risk of infection
  • Performing splenectomy to remove the spleen
  • Performing a bone marrow transplant to replace the damaged spleen
  • Removing the spleen and replacing it with a healthy spleen from another person
  • Administering intravenous immunoglobulin (IVIG) to boost the immune system
  • Performing stem cell transplants to replace the damaged spleen
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16 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Hyposplenism - Prevention

Hyposplenism can be prevented by addressing the underlying cause of the condition, such as managing any underlying medical conditions, avoiding contact with people who are sick, and practicing good hygiene. vaccinating against certain bacterial infections, such as meningococcal infection, can also help to reduce the risk of developing hyposplenism.

Main symptoms of the disease hyposplenism

Dizziness

(Vertigo, Lightheadedness, Giddiness, Faintness, Unsteadiness, Dazed, Spinning, Disorientation, Unbalanced, Foggy, Loss of balance, Uncoordinated, Confusion)

Dizziness is a sensation of feeling off-balance and lightheaded. It can range from mild to severe and can be accompanied by a feeling of spinning or swaying. It can develop suddenly or gradually, and can be triggered by physical activity, changes in position, or lack of food or fluids. Symptoms can ...

Age: 1 to 100Accociated with 133 diseases

Muscle weakness

(Aching muscles, Lack of strength, Muscular fatigue, Decreased muscle power, Reduced muscle tone, Muscle exhaustion, Muscle debility, Lack of muscle control, Lack of muscular coordination, Loss of muscle strength)

Muscle weakness is a decrease in the strength of the muscles that can lead to difficulty in performing everyday tasks. It can manifest in a variety of ways, including fatigue, difficulty walking, and reduced range of motion. It can develop gradually or suddenly, and can be caused by a variety of med...

Age: 0 to 99Accociated with 47 diseases

Decreased appetite

(Diminished hunger, Loss of appetite, Lack of appetite, Decreased hunger, Reduced appetite, Anorexia, Poor appetite, Decreased intake, Lack of interest in food)

Decreased appetite is a symptom that can manifest in a variety of ways. It can manifest as a lack of interest in food, difficulty eating, or a lack of hunger. This symptom can develop gradually over time or suddenly. It can be caused by a variety of medical conditions, medications, or psychological ...

Age: any ageAccociated with 119 diseases

High pressure

(Hypertension, Hypertensive, High blood pressure, Bp, Elevated pressure, Raised pressure, Cardiac stress, Tension, Strain)

High pressure headache is a type of headache that is characterized by a feeling of pressure or tightness around the head. It usually develops slowly, beginning as a dull ache and gradually intensifying to a throbbing or pounding sensation. It can be accompanied by other symptoms such as sensitivity ...

Age: any ageAccociated with 59 diseases

Nausea

(Upset stomach, Queasiness, Queasy feeling, Stomach discomfort, Gastric unease, Stomach churning, Stomach upset, Stomachache, Feeling sick, Feeling queasy, Stomach queasiness, Feeling nauseous, Feeling nauseated, Nauseousness)

Nausea is an unpleasant feeling in the upper abdomen that may be accompanied by an urge to vomit. It can range from mild to severe and can be accompanied by symptoms such as sweating, dizziness, and increased salivation. Nausea can be caused by a variety of stimuli, including motion sickness, certai...

Age: 1 to 100Accociated with 217 diseases

Heartburn

(Acid reflux, Indigestion, Pyrosis, Gerd, Upset stomach, Burning sensation, Acid indigestion)

Heartburn is a burning sensation in the chest caused by acid reflux from the stomach into the esophagus. It often starts as a mild discomfort after eating and can become worse over time. Symptoms can range from a burning sensation in the chest to a sour taste in the mouth. It may also be accompanied...

Age: 1 to 100Accociated with 22 diseases

Headache

(Cephalalgia, Hedache, Pounding head, Throbbing head, Ache, Pounding pain, Throbbing pain, Head pain, Migraine, Tension headache)

Headache is a common symptom that can range from mild to severe. It typically develops gradually and can be localized or generalized. Common types of headache include tension-type, migraine, cluster, and sinus headaches, each with their own unique characteristics and manifestations. Tension-type hea...

Age: 1 to 100Accociated with 244 diseases

Fatigue

(Tiredness, Exhaustion, Lethargy, Lassitude, Weariness, Burn-out, Weakness, Malaise, Lack of energy, Lack of strength, Listlessness)

Fatigue is a common symptom that can range from mild to severe. It is usually characterized by a feeling of tiredness and exhaustion that can range from mild to severe. It can develop gradually over time or suddenly, and can be caused by a variety of factors, including physical or mental stress, sle...

Age: 1 to 100Accociated with 157 diseases

Weakness

Weakness is a lack of strength and energy that can range from mild to severe. It can be a symptom of a wide range of conditions, including physical and mental exhaustion, chronic illnesses, and certain medications. It can also be caused by a lack of nutrients, dehydration, or an underlying medical c...

Age: any ageAccociated with 291 diseases