(D74.9) Methaemoglobinaemia, unspecified

More details coming soon

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4 596 in individuals diagnosis methaemoglobinaemia, unspecified confirmed
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3 577 deaths with diagnosis methaemoglobinaemia, unspecified
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78% mortality rate associated with the disease methaemoglobinaemia, unspecified

Diagnosis methaemoglobinaemia, unspecified is diagnosed Women are 24.98% more likely than Men

1 724

Men receive the diagnosis methaemoglobinaemia, unspecified

0 (less than 0.1%)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
20
15
10
5
0
2 872

Women receive the diagnosis methaemoglobinaemia, unspecified

3 577 (124.5 %)

Died from this diagnosis.

Risk Group for the Disease methaemoglobinaemia, unspecified - Men and Women aged 0

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In Men diagnosis is most often set at age 0-5, 20-24, 35-39, 50-59, 65-69
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Less common in men the disease occurs at Age 5-19, 25-34, 40-49, 60-64, 70-95+Less common in women the disease occurs at Age 0-5, 10-14, 25-54, 70-74, 80-95+
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In Women diagnosis is most often set at age 0-1, 5-9, 15-24, 55-69, 75-79

Disease Features methaemoglobinaemia, unspecified

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Non-contagious
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High individual and public risk
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Methaemoglobinaemia, unspecified - what does this mean

Methaemoglobinaemia is a condition in which there is an abnormally high level of methaemoglobin in the blood. it is caused by a genetic defect in the production of the enzyme cytochrome b5 reductase, or by exposure to certain drugs and chemicals, such as nitrites, nitrates, and certain aniline dyes. symptoms can include fatigue, headache, dizziness, shortness of breath, and a bluish discoloration of the skin. treatment involves the removal of the offending agent and the administration of methylene blue or other reducing agents.

What happens during the disease - methaemoglobinaemia, unspecified

Methaemoglobinaemia is an inherited disorder in which the oxygen-carrying protein in the red blood cells, haemoglobin, is abnormally oxidised to form methaemoglobin. this oxidised form of haemoglobin is unable to bind and transport oxygen, leading to a decrease in oxygen levels in the body and resulting in a range of symptoms, including headache, fatigue, dizziness, shortness of breath, and cyanosis. the condition can be caused by a genetic mutation, exposure to certain drugs or toxins, or acquired from a blood transfusion.

Clinical Pattern

More details coming soon

How does a doctor diagnose

  • Complete physical examination
  • Blood tests to measure the levels of haemoglobin and methaemoglobin
  • Urine tests to measure the levels of haemoglobin and methaemoglobin
  • Chest X-ray to check for any underlying causes
  • CT scan to check for any underlying causes
  • MRI scan to check for any underlying causes
  • Treatment with methylene blue if the levels of methaemoglobin are high

Treatment and Medical Assistance

Main goal of the treatment: To reduce the amount of methaemoglobin in the patient's blood.
  • Administer oxygen therapy
  • Administer methylene blue
  • Administer ascorbic acid
  • Administer hydroxycobalamin
  • Administer exchange transfusion
  • Administer hyperbaric oxygen therapy
  • Perform supportive care
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10 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Methaemoglobinaemia, unspecified - Prevention

Methaemoglobinaemia, unspecified can be prevented by avoiding exposure to certain drugs and chemicals that can cause the condition, such as nitrates, nitrites, and aniline dyes. additionally, it is important to ensure that any medications prescribed to treat other medical conditions do not contain these substances, and to consult with a healthcare provider before taking any new medications.

Main symptoms of the disease methaemoglobinaemia, unspecified

Skull deformity

(Skull malformation, Cranial abnormality, Craniofacial anomaly, Craniosynostosis, Craniofacial dysplasia, Cranial deformity, Head deformity, Skull abnormality, Skull defect)

Skull deformity is a condition where the shape or size of the skull is abnormally altered. It can be present at birth or develop over time. Signs and symptoms may include an unusually shaped head, bulging eyes, unequal head size, and an inability to move the head in certain directions. It may also c...

Age: At null Years OldAccociated with 3 diseases
Changing the structure of nails

Changing the structure of nails

(Aches, Agony, Anguish, Distress, Hurt, Misery, Pain, Soreness, Suffering, Torture, Trouble, Woe)

Changing the structure of nails is a symptom that can manifest in various ways, such as the nails becoming thick, brittle, or curved. It can also appear as discoloration, ridges, and spotting. This symptom usually develops slowly over time and can be caused by numerous factors, such as underlying me...

Age: any ageAccociated with 10 diseases

Dizziness

(Vertigo, Lightheadedness, Giddiness, Faintness, Unsteadiness, Dazed, Spinning, Disorientation, Unbalanced, Foggy, Loss of balance, Uncoordinated, Confusion)

Dizziness is a sensation of feeling off-balance and lightheaded. It can range from mild to severe and can be accompanied by a feeling of spinning or swaying. It can develop suddenly or gradually, and can be triggered by physical activity, changes in position, or lack of food or fluids. Symptoms can ...

Age: 1 to 100Accociated with 133 diseases

Heart rhythm disorder

(Arrhythmia, Cardiac arrhythmia, Irregular heartbeat, Cardiac dysrhythmia, Cardiac rhythm disorder, Heart rhythm disturbance, Heart rhythm irregularity, Cardiac rhythm irregularity, Abnormal heartbeat, Heartbeat disorder)

Heart rhythm disorder is a condition where the heart beats irregularly or too quickly or too slowly. It can manifest as palpitations, lightheadedness, chest pain, fatigue, or shortness of breath. It can develop from a variety of causes, including lifestyle factors, medications, and underlying medica...

Age: any ageAccociated with 48 diseases

Tachycardia

(Rapid heartbeat, Fast heartbeat, Accelerated heart rate, High heart rate, Increased heart rate, Abnormal heart rhythm, Palpitations)

Tachycardia is a rapid heart rate, usually defined as a rate greater than 100 beats per minute. It is usually caused by a disruption of the normal electrical signals that control the heart's rhythm. Symptoms may include palpitations, chest pain, shortness of breath, lightheadedness, or dizziness. It...

Age: 1 to 100Accociated with 90 diseases

Cyanosis

(Bluish skin, Blue skin, Blue discoloration, Blue tint, Blue hue, Bluish tinge, Cyanotic discoloration, Cyanotic hue, Cyanotic tint, Cyanotic skin, Blue-tinged skin)

Cyanosis is a medical symptom characterized by a bluish discoloration of the skin and mucous membranes, due to a lack of oxygen in the blood. It is most commonly seen around the lips, fingers, and toes, and can range in severity from mild to life-threatening. Early signs may include a faint bluish t...

Age: any ageAccociated with 79 diseases

Rapid breathing

(Hyperventilation, Tachypnea, Panting, Shortness of breath, Labored breathing, Fast breathing, Hyperpnea, Respiratory distress)

Rapid breathing is a symptom where a person breathes faster than normal. It is usually characterized by shallow, short breaths taken at a rate of more than 20 breaths per minute. This symptom can develop suddenly or gradually, and can be caused by a variety of factors, including anxiety, asthma, inf...

Age: 1 to 100Accociated with 30 diseases

Delayed stages of development

(Retardation, Sluggishness, Arrested growth, Backwardness, Lateness, Stunted growth, Slow progress, Lag, Slowness, Stagnation)

Delayed stages of development is a symptom where a person is not meeting the expected milestones for their age. It can manifest as a lack of certain skills, such as speech, physical coordination, or cognitive abilities. It can also appear as a slower rate of development than peers, such as taking lo...

Age: 1 to 100Accociated with 19 diseases

Headache

(Cephalalgia, Hedache, Pounding head, Throbbing head, Ache, Pounding pain, Throbbing pain, Head pain, Migraine, Tension headache)

Headache is a common symptom that can range from mild to severe. It typically develops gradually and can be localized or generalized. Common types of headache include tension-type, migraine, cluster, and sinus headaches, each with their own unique characteristics and manifestations. Tension-type hea...

Age: 1 to 100Accociated with 244 diseases

Dyspnea

(Shortness of breath, Labored breathing, Breathlessness, Air hunger, Difficulty breathing, Gasping, Panting, Wheezing, Tightness in chest, Suffocating feeling)

Dyspnea is a feeling of breathlessness or difficulty breathing. It can range from mild to severe and can be caused by a variety of factors, such as asthma, COPD, heart failure, or anemia. Symptoms of dyspnea may include shortness of breath, wheezing, chest tightness, and rapid breathing. Dyspnea can...

Age: 1 to 100Accociated with 155 diseases

Spasm

(Twitching, Contraction, Cramp, Jerking, Convulsion, Muscle spasm, Tic, Clonus, Myoclonus, Spasmodic)

A spasm is a sudden, involuntary muscle contraction that can cause pain and discomfort. It can occur in any muscle group and can be caused by a variety of different conditions. Symptoms of a spasm can include tightness, pain, and difficulty moving the affected muscle. Spasms can develop suddenly or ...

Age: 1 to 100Accociated with 56 diseases

Coma

(Unconsciousness, Stupor, Vegetative state, Profound unconsciousness, Deep sleep, Deep unconsciousness, Persistent vegetative state, Locked-in syndrome)

Coma is a state of unconsciousness in which a person cannot be awakened, fails to respond normally to painful stimuli, light, or sound, lacks a normal wake-sleep cycle, and does not initiate voluntary actions. It usually develops gradually over a period of time, and can be caused by a variety of med...

Age: 1 to 100Accociated with 19 diseases

Fainting

(Syncope, Swoon, Passing out, Losing consciousness, Blackout, Dizziness, Unconsciousness)

Fainting is a sudden, brief loss of consciousness and muscle tone, usually caused by a drop in blood pressure. It is often accompanied by a feeling of dizziness, lightheadedness, and confusion. Fainting usually occurs in response to a sudden emotional or physical stressor, such as standing for a lon...

Age: 1 to 100Accociated with 56 diseases

Weakness

Weakness is a lack of strength and energy that can range from mild to severe. It can be a symptom of a wide range of conditions, including physical and mental exhaustion, chronic illnesses, and certain medications. It can also be caused by a lack of nutrients, dehydration, or an underlying medical c...

Age: any ageAccociated with 291 diseases