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(D81.6) Major histocompatibility complex class i deficiency
More details coming soon
37 763 in individuals diagnosis major histocompatibility complex class i deficiency confirmed
2 729 deaths with diagnosis major histocompatibility complex class i deficiency
7% mortality rate associated with the disease major histocompatibility complex class i deficiency
Diagnosis major histocompatibility complex class i deficiency is diagnosed Men are 25.48% more likely than Women
23 693
Men receive the diagnosis major histocompatibility complex class i deficiency
926 (3.9 %)Died from this diagnosis.
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14 070
Women receive the diagnosis major histocompatibility complex class i deficiency
1 803 (12.8 %)Died from this diagnosis.
Risk Group for the Disease major histocompatibility complex class i deficiency - Men aged 20-24 and Women aged 0-5
In Men diagnosis is most often set at age 0-14, 20-89
Less common in men the disease occurs at Age 15-19, 90-95+Less common in women the disease occurs at Age 55-59, 90-95+
In Women diagnosis is most often set at age 0-54, 60-89
Disease Features major histocompatibility complex class i deficiency
Absence or low individual and public risk
Major histocompatibility complex class i deficiency - what does this mean
Major histocompatibility complex class i deficiency is an inherited disorder caused by mutations in the genes that encode the proteins of the major histocompatibility complex (mhc) class i. these proteins are responsible for presenting antigens to the immune system, and when they are not functioning correctly, the body is unable to mount a normal immune response and is at increased risk for infections and other diseases.
What happens during the disease - major histocompatibility complex class i deficiency
Major histocompatibility complex class i deficiency is caused by a mutation in the genes responsible for the production of mhc class i molecules, which are essential for the normal functioning of the immune system. this deficiency leads to a weakened immune system, making the individual more susceptible to infections and other autoimmune disorders.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Complete Blood Count (CBC)
- Flow cytometry
- Lymphocyte proliferation assay
- T-cell receptor gene rearrangement assay
- Immunoglobulin levels
- Serum cytokine levels
- Skin biopsy
- X-ray
Treatment and Medical Assistance
Main goal of the treatment: Improve the body's ability to fight infection.
- Administer immunoglobulin therapy
- Prescribe antibiotics to treat existing infections
- Provide vaccinations to prevent future infections
- Prescribe antiviral medications to treat viral infections
- Prescribe antifungal medications to treat fungal infections
- Prescribe anti-parasitic medications to treat parasitic infections
- Provide nutritional support to improve overall health
- Monitor patient's health closely
19 Days of Hospitalization Required
48 Hours Required for Outpatient Treatment
Major histocompatibility complex class i deficiency - Prevention
Major histocompatibility complex class i deficiency can be prevented by avoiding exposure to environmental toxins, eating a balanced diet rich in fruits and vegetables, exercising regularly, and maintaining proper hygiene. vaccines can also help prevent mhci deficiency by providing immunity to certain viruses and bacteria.