(D89.1) Cryoglobulinaemia

More details coming soon

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174 863 in individuals diagnosis cryoglobulinaemia confirmed
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7 103 deaths with diagnosis cryoglobulinaemia
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4% mortality rate associated with the disease cryoglobulinaemia

Diagnosis cryoglobulinaemia is diagnosed Women are 22.25% more likely than Men

67 982

Men receive the diagnosis cryoglobulinaemia

4 498 (6.6 %)

Died from this diagnosis.

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106 881

Women receive the diagnosis cryoglobulinaemia

2 605 (2.4 %)

Died from this diagnosis.

Risk Group for the Disease cryoglobulinaemia - Men aged 60-64 and Women aged 50-54

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In Men diagnosis is most often set at age 0-89
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Less common in men the disease occurs at Age 90-95+Less common in women the disease occurs at Age 90-95+
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In Women diagnosis is most often set at age 0-89

Disease Features cryoglobulinaemia

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Non-contagious
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Moderate individual risk, low public risk
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Cryoglobulinaemia - what does this mean

Cryoglobulinaemia is a disease caused by the accumulation of abnormal proteins in the blood called cryoglobulins. these proteins can cause inflammation, clotting, and blockage of small blood vessels, leading to a variety of symptoms including fatigue, joint pain, skin rash, and kidney problems.

What happens during the disease - cryoglobulinaemia

Cryoglobulinaemia is a disorder in which abnormal proteins, called cryoglobulins, form in the bloodstream. these proteins can cause inflammation in small blood vessels, leading to a range of symptoms including joint pain, skin rashes, and kidney damage. the underlying cause of cryoglobulinaemia is not known, but it is thought to be related to a combination of genetic and environmental factors. in some cases, it may be triggered by an infection or autoimmune disorder.

Clinical Pattern

More details coming soon

How does a doctor diagnose

  • Complete Blood Count (CBC) with differential
  • Serum protein electrophoresis
  • Serum immunofixation electrophoresis
  • Quantitative immunoglobulins
  • Cryoprecipitate analysis
  • Serum cryoglobulins
  • Liver function tests
  • Kidney function tests
  • Viral serology
  • Rheumatoid factor
  • Hepatitis B and C testing
  • Skin biopsy

Treatment and Medical Assistance

Main goal of the treatment: To reduce symptoms and prevent complications of cryoglobulinaemia.
  • Monitoring of the patient's health status
  • Medication to reduce inflammation and suppress the immune system
  • Blood transfusions to replace lost blood cells
  • Plasmapheresis to remove excess cryoglobulins
  • Low-dose chemotherapy to reduce the amount of cryoglobulins
  • Immunosuppressive therapy to reduce the body's production of cryoglobulins
  • Antibiotics to treat any infections
  • Vaccinations to prevent infections
  • Avoiding exposure to cold temperatures
  • Regular exercise to maintain physical fitness
  • Healthy eating habits to maintain a balanced diet
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11 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Cryoglobulinaemia - Prevention

Cryoglobulinaemia can be prevented by avoiding exposure to certain medications, such as antibiotics, and by avoiding contact with people who have active infections. it is also important to avoid activities that may cause trauma to the blood vessels, such as contact sports. vaccinations are also important in preventing certain infections that can cause cryoglobulinaemia. finally, regular medical check-ups are important in order to identify any early signs of the disease.

Main symptoms of the disease cryoglobulinaemia

Muscle pain

(Muscle ache, Muscular soreness, Muscular discomfort, Muscle tenderness, Muscle strain, Muscle spasm, Muscle twinge, Muscle stiffness, Muscle cramp, Muscle fatigue)

Muscle pain is a symptom of an underlying medical condition. It can range from a dull ache to a sharp, burning sensation and can be localized to one area or throughout the body. It often develops gradually, starting with mild discomfort that progresses over time. Muscle pain can be caused by a varie...

Age: 1 to 100Accociated with 88 diseases

Joint pain

(Arthritis, Rheumatism, Aches, Stiffness, Inflammation, Tenderness, Soreness, Swollen joints, Stabbing pain, Throbbing pain, Sharp pain, Dull ache)

Joint pain is a common symptom that can range from mild to severe. It is often caused by inflammation or injury to the joints, muscles, or tendons. It can be localized to one joint or affect multiple joints. It can be acute, lasting only a few days or chronic, lasting weeks or months. It may manifes...

Age: any ageAccociated with 130 diseases

Skin numbness

(Loss of sensation, Lack of sensation, Anesthesia, Paralysis, Paraesthesia, Neuralgia, Hypoesthesia, Paresthesia, Tingling, Numbness, Loss of feeling)

Skin numbness is a condition where the skin has lost its sensation. It can manifest as a tingling or burning sensation, or as a complete lack of feeling. It can develop suddenly or gradually, and can affect any area of the body. It can be caused by nerve damage, diabetes, or other medical conditions...

Age: 1 to 100Accociated with 18 diseases
Rash

Rash

(Eruption, Dermatitis, Skin irritation, Hives, Itching, Inflammation, Redness, Bumps, Blotches, Scaly patch)

A rash is an area of irritated or swollen skin. It may appear as red bumps, patches, or blisters and can be itchy, dry, or painful. It can develop suddenly or over time and can be caused by a variety of factors, including allergies, infections, and irritants. Common rashes include eczema, hives, and...

Age: any ageAccociated with 103 diseases
Darkening of tissues

Darkening of tissues

Darkening of tissues is a symptom that occurs when tissues in the body become discolored and darker in color. It can occur in any part of the body, including the skin, eyes, and mucous membranes. It is usually caused by an increase in the amount of melanin in the tissue, but can also be caused by ot...

Age: 1 to 100Accociated with 13 diseases

High pressure

(Hypertension, Hypertensive, High blood pressure, Bp, Elevated pressure, Raised pressure, Cardiac stress, Tension, Strain)

High pressure headache is a type of headache that is characterized by a feeling of pressure or tightness around the head. It usually develops slowly, beginning as a dull ache and gradually intensifying to a throbbing or pounding sensation. It can be accompanied by other symptoms such as sensitivity ...

Age: any ageAccociated with 59 diseases

General edema

(Swelling, Water retention, Bloating, Puffiness, Inflammation, Fluid retention, Hydrops, Dropsy, Oedema, Hydrothorax)

General edema is swelling caused by excess fluid trapped in the body's tissues. It can affect any part of the body, but is most noticeable in the feet, ankles, legs, hands, and face. It can develop suddenly or gradually. Symptoms range from mild to severe, and may include pain, itching, or a feeling...

Age: any ageAccociated with 50 diseases

Anuria and oliguria

(Absence of urine, Decreased urine output, Low urine output, Reduced urine production, Suppressed urine production)

Anuria and oliguria are medical terms used to describe a decreased output of urine. Anuria is a complete absence of urine and oliguria is a decreased output of urine. These symptoms can be caused by a number of conditions, such as kidney failure, dehydration, or blockage in the urinary tract. Sympto...

Age: 1 to 100Accociated with 37 diseases
Ulcer external

Ulcer external

(Open sore, Lesion, Sore, Cut, Wound, Gash, Abrasion, Laceration, Scratch, Bruise)

Ulcer external is a type of skin lesion that is caused by a break in the skin, leading to an open sore. It usually appears as a red, raised area that is often painful and may have a yellowish or white pus-filled center. The area around the ulcer may be swollen and warm to the touch. Ulcer external c...

Age: 1 to 100Accociated with 39 diseases