(E85.4) Organ-limited amyloidosis

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102 222 in individuals diagnosis organ-limited amyloidosis confirmed
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52 500 deaths with diagnosis organ-limited amyloidosis
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51% mortality rate associated with the disease organ-limited amyloidosis

Diagnosis organ-limited amyloidosis is diagnosed Men are 6.07% more likely than Women

54 214

Men receive the diagnosis organ-limited amyloidosis

32 453 (59.9 %)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
50
45
40
35
30
25
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15
10
5
0
48 008

Women receive the diagnosis organ-limited amyloidosis

20 047 (41.8 %)

Died from this diagnosis.

Risk Group for the Disease organ-limited amyloidosis - Men and Women aged 70-74

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In Men diagnosis is most often set at age 0-14, 20-94
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Less common in men the disease occurs at Age 0-1, 15-19, 95+Less common in women the disease occurs at Age 0-1, 95+
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In Women diagnosis is most often set at age 0-94

Disease Features organ-limited amyloidosis

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Absence or low individual and public risk
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Organ-limited amyloidosis - what does this mean

Organ-limited amyloidosis is a rare condition in which abnormal proteins, known as amyloid, accumulate in certain organs of the body, such as the heart, kidneys, and liver. this accumulation of amyloid proteins in the organs can lead to organ dysfunction and failure.

What happens during the disease - organ-limited amyloidosis

Organ-limited amyloidosis is a condition in which amyloid proteins accumulate and deposit in specific organs or tissues, such as the heart, kidney, liver, or spleen. the exact cause of the condition is unknown, but it is believed to be caused by an abnormal production of amyloid proteins, which are produced from abnormal forms of a protein known as transthyretin. these abnormal proteins are then deposited in the organs and tissues, leading to the malfunction of the affected organs and tissues.

Clinical Pattern

More details coming soon

How does a doctor diagnose

  • Complete physical examination
  • Blood tests
  • Urine tests
  • X-ray
  • CT scan
  • MRI scan
  • Echocardiogram
  • Bone marrow biopsy
  • Electrocardiogram (ECG)
  • Positron emission tomography (PET) scan
Additions:
  • Liver biopsy
  • Kidney biopsy

Treatment and Medical Assistance

Main goal of the treatment: To reduce the amount of amyloid deposits in the organs and improve the patient's quality of life.
  • Early diagnosis and monitoring of the disease
  • Treatment of the underlying cause of the amyloidosis
  • Medications to reduce inflammation and organ damage
  • Lifestyle changes such as a balanced diet and regular exercise
  • Regular blood tests to monitor the disease progression
  • Regular check-ups to monitor organ function
  • Surgery to remove amyloid deposits from the organs
  • Immunosuppressive therapy to reduce inflammation and organ damage
  • Stem cell transplantation to replace damaged organs
  • Plasmapheresis to remove amyloid deposits from the blood
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19 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Organ-limited amyloidosis - Prevention

Organ-limited amyloidosis can be prevented by controlling and managing any underlying conditions that can cause amyloid deposits, such as diabetes, kidney disease, and rheumatoid arthritis. additionally, maintaining a healthy lifestyle by eating a balanced diet, exercising regularly, and avoiding smoking can help reduce the risk of developing organ-limited amyloidosis.