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(L10.5) Drug-induced pemphigus
More details coming soon
190 040 in individuals diagnosis drug-induced pemphigus confirmed
3 763 deaths with diagnosis drug-induced pemphigus
2% mortality rate associated with the disease drug-induced pemphigus
Diagnosis drug-induced pemphigus is diagnosed Women are 15.67% more likely than Men
80 132
Men receive the diagnosis drug-induced pemphigus
1 911 (2.4 %)Died from this diagnosis.
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109 908
Women receive the diagnosis drug-induced pemphigus
1 852 (1.7 %)Died from this diagnosis.
Risk Group for the Disease drug-induced pemphigus - Men aged 55-59 and Women aged 60-64
In Men diagnosis is most often set at age 0-1, 5-89
Less common in men the disease occurs at Age 0-5, 90-95+in in women, the disease manifests at any age
In Women diagnosis is most often set at age 0-95+
Disease Features drug-induced pemphigus
Absence or low individual and public risk
Drug-induced pemphigus - what does this mean
Drug-induced pemphigus is an autoimmune disorder that occurs when a person takes a medication that triggers an immune system response causing the body to produce antibodies that attack healthy skin cells, leading to painful blisters and open sores on the skin and mucous membranes.
What happens during the disease - drug-induced pemphigus
Drug-induced pemphigus is an autoimmune disorder triggered by certain medications, such as antibiotics, anticonvulsants, and non-steroidal anti-inflammatory drugs. the drugs trigger the production of autoantibodies which attack and destroy the desmosomes, a type of cell junction, in the skin and mucous membranes. this leads to the formation of blisters and erosions in the affected areas.
Clinical Pattern
More details coming soon
How does a doctor diagnose
- Physical examination of the affected areas
- Skin biopsy
- Blood tests to check for autoantibodies
- Tissue culture test
- Immunofluorescence test
- Drug-induced pemphigus-specific antibody tests
- Imaging tests such as X-rays or CT scans
Treatment and Medical Assistance
Main goal of the treatment: To reduce the severity of symptoms and reduce the risk of complications.
- Prescribing medications to reduce inflammation and suppress the immune system.
- Providing topical and/or systemic corticosteroids.
- Prescribing immunosuppressants to reduce the activity of the immune system.
- Prescribing antibiotics to treat bacterial infections.
- Prescribing antivirals to treat viral infections.
- Providing topical and/or systemic antifungal medications to treat fungal infections.
- Providing topical and/or systemic antihistamines to reduce itching.
- Providing topical and/or systemic moisturizers to reduce dryness.
- Providing phototherapy to reduce inflammation.
- Providing physical therapy to reduce pain and improve mobility.
- Providing lifestyle advice to reduce stress and improve overall health.
15 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Drug-induced pemphigus - Prevention
Drug-induced pemphigus can be prevented by avoiding the use of medications that are known to trigger the disease, such as certain antibiotics, anti-convulsants, and diuretics. additionally, it is important to consult with a physician before beginning any new medication, and to be aware of any potential side effects.